This composite image illustrates a portable, AI-integrated system for the real-time detection of Trypanosoma cruzi in laboratory settings. The left panel displays a close-up of the AI algorithm’s output on a smartphone screen, with bounding boxes drawn around the detected parasites. The right panel provides the operational context, showing a technician using the AI-augmented mobile microscopy system at the Facultad de Medicina, Universidad Mayor de San Simón (Cochabamba, Bolivia). Lin et al. 2026
Image Credit: Mary Cruz Torrico, Facultad de Medicina, Universidad Mayor de San Simón, Cochabamba, Bolivia
Viewpoints
Hiding in plain sight: A call to prevent cutaneous leishmaniasis transmission in the United States
PLOS Neglected Tropical Diseases: published May 8, 2026 | https://doi.org/10.1371/journal.pntd.0014297
Cholera in Africa: Current trends, challenges, and control towards elimination strategies
PLOS Neglected Tropical Diseases: published May 28, 2026 | https://doi.org/10.1371/journal.pntd.0014325
Policy Platform
From invisibility to political power: Policy lessons from a decade of Brazil’s Social Forum for Infectious and Neglected Diseases
PLOS Neglected Tropical Diseases: published May 29, 2026 | https://doi.org/10.1371/journal.pntd.0014336
Reviews
Mycetoma
PLOS Neglected Tropical Diseases: published May 15, 2026 | https://doi.org/10.1371/journal.pntd.0014291
Zoonotic leishmaniasis in China: Current status and challenges to elimination
PLOS Neglected Tropical Diseases: published May 21, 2026 | https://doi.org/10.1371/journal.pntd.0014344
Neglected rickettsial diseases in Southeast Asia: Twenty-five years of progress in surveillance, diagnostics, and clinical research
PLOS Neglected Tropical Diseases: published May 26, 2026 | https://doi.org/10.1371/journal.pntd.0014318
Research Articles
Sire risk factors for vertical transmission of Leishmania infantum by the dam
PLOS Neglected Tropical Diseases: published May 4, 2026 | https://doi.org/10.1371/journal.pntd.0014303
The hydatid cyst fluid protein EgAgB8/1 demonstrates potent immunogenicity by eliciting robust humoral and cellular immune responses in mice
PLOS Neglected Tropical Diseases: published May 4, 2026 | https://doi.org/10.1371/journal.pntd.0014260
Dual role of Japanese encephalitis virus fusion loop peptide antibodies in Zika virus infection
PLOS Neglected Tropical Diseases: published May 4, 2026 | https://doi.org/10.1371/journal.pntd.0014296
Epidemiology and risk factors of soil-transmitted nematode-schistosome co-occurrence: An analysis of the global burden of disease study
PLOS Neglected Tropical Diseases: published May 4, 2026 | https://doi.org/10.1371/journal.pntd.0014224
Establishment and characterization of a Wolbachia (wAlbB)-infected Aedes aegypti line (Tw-Kao) for dengue control
PLOS Neglected Tropical Diseases: published May 4, 2026 | https://doi.org/10.1371/journal.pntd.0014222
Modelling approaches for predicting the distribution of skin NTDs: A systematic review
PLOS Neglected Tropical Diseases: published May 4, 2026 | https://doi.org/10.1371/journal.pntd.0013662
Methods for estimating the burden of acute tropical infectious diseases: A scoping review
PLOS Neglected Tropical Diseases: published May 4, 2026 | https://doi.org/10.1371/journal.pntd.0013359
Chikungunya virus in dengue-suspected patients: Molecular evidence from the 2019 outbreak in Yangon, Myanmar
PLOS Neglected Tropical Diseases: published May 4, 2026 | https://doi.org/10.1371/journal.pntd.0014258
AIDS patients with Talaromycosis Marneffei exhibit inflammatory activation and depletion in their peripheral blood monocytes
PLOS Neglected Tropical Diseases: published May 4, 2026 | https://doi.org/10.1371/journal.pntd.0014306
Biomphalaria pfeifferi infected with Schistosoma spp. in Kakamega and Bungoma counties, western Kenya confirms autochthonous transmission of intestinal schistosomiasis
PLOS Neglected Tropical Diseases: published May 4, 2026 | https://doi.org/10.1371/journal.pntd.0014276
Syndromic management of sexually transmitted infections in the Brazilian Amazon: A 10-year retrospective study
PLOS Neglected Tropical Diseases: published May 4, 2026 | https://doi.org/10.1371/journal.pntd.0014282
Field deployment of a mobile suitcase laboratory for Buruli ulcer diagnosis in Ghana
PLOS Neglected Tropical Diseases: published May 4, 2026 | https://doi.org/10.1371/journal.pntd.0013683
Incidence of acute pancreatitis among hospitalized patients with dengue: A systematic review and meta-analysis
PLOS Neglected Tropical Diseases: published May 4, 2026 | https://doi.org/10.1371/journal.pntd.0014304
Clonorchis sinensis excretory secretory products promote hepatic fibrosis through stimulating biliary epithelium to secrete IL-17A
PLOS Neglected Tropical Diseases: published May 5, 2026 | https://doi.org/10.1371/journal.pntd.0014280
Global, regional, and national disease burden of arthropod-borne diseases: Projections to 2030 based on the global burden of disease study 2021
PLOS Neglected Tropical Diseases: published May 5, 2026 | https://doi.org/10.1371/journal.pntd.0014235
Diagnostic performance of a biotin-labeled 4D1 sandwich ELISA for serum antigen detection in talaromycosis
PLOS Neglected Tropical Diseases: published May 5, 2026 | https://doi.org/10.1371/journal.pntd.0014314
Accuracy of AI-assisted diagnostic tools for Schistosoma haematobium: A systematic review and meta-analysis
PLOS Neglected Tropical Diseases: published May 5, 2026 | https://doi.org/10.1371/journal.pntd.0013703
Sequential Organ Failure Assessment (SOFA) score and quick SOFA(qSOFA) predict 30-day mortality in patients with HIV-associated Talaromycosis: A multicenter retrospective cohort study
PLOS Neglected Tropical Diseases: published May 5, 2026 | https://doi.org/10.1371/journal.pntd.0014278
Epidemiological study of leptospiral interaction in bovine farms in rural areas of Colombia: A One Health approach
PLOS Neglected Tropical Diseases: published May 6, 2026 | https://doi.org/10.1371/journal.pntd.0014231
Mycetoma as a major cause of limb amputation in Northeastern Ethiopia: A facility-based retrospective study
PLOS Neglected Tropical Diseases: published May 6, 2026 | https://doi.org/10.1371/journal.pntd.0013886
Mass drug administration for soil-transmitted helminthiasis and schistosomiasis in selected districts of Rwanda: Coverage, implementation factors, and household water, sanitation, and hygiene conditions
PLOS Neglected Tropical Diseases: published May 7, 2026 | https://doi.org/10.1371/journal.pntd.0014267
Artificial intelligence algorithm for real-time detection and counting of Trypanosoma cruzi parasites using smartphone microscopy
PLOS Neglected Tropical Diseases: published May 7, 2026 | https://doi.org/10.1371/journal.pntd.0012955
Diagnostic performance of the TR Chagas Bio-Manguinhos rapid test for detecting anti-Trypanosoma cruzi IgG in human samples from three Southern Cone countries
PLOS Neglected Tropical Diseases: published May 8, 2026 | https://doi.org/10.1371/journal.pntd.0014310
Experimental protothecosis in a murine model
PLOS Neglected Tropical Diseases: published May 11, 2026 | https://doi.org/10.1371/journal.pntd.0014312
Furuncular myiasis by Cordylobia anthropophaga in three Italian children: First case series and implications for non-endemic regions
PLOS Neglected Tropical Diseases: published May 11, 2026 | https://doi.org/10.1371/journal.pntd.0013535
Three Leishmania species identified in domestic dogs in Tunisia: New insights into canine leishmaniosis
PLOS Neglected Tropical Diseases: published May 11, 2026 | https://doi.org/10.1371/journal.pntd.0014299
Mapping the last mile: Micro-stratification for sustained visceral leishmaniasis elimination in Bangladesh
PLOS Neglected Tropical Diseases: published May 11, 2026 | https://doi.org/10.1371/journal.pntd.0013504
Outbreak of dengue fever in Ghana: The emergence of DENV-1 serotype
PLOS Neglected Tropical Diseases: published May 11, 2026 | https://doi.org/10.1371/journal.pntd.0014248
Leptospirosis-associated meningitis in an urban tropical endemic setting in northeastern Brazil: Three New cases and a meta-summary of 176 reported cases
PLOS Neglected Tropical Diseases: published May 11, 2026 | https://doi.org/10.1371/journal.pntd.0014315
Development of novel monoclonal antibodies for detection of pan-Lassa virus
PLOS Neglected Tropical Diseases: published May 11, 2026 | https://doi.org/10.1371/journal.pntd.0014326
Identification and genetic characterization of a distinct genotype of Puumala orthohantavirus in Hebei Province, China
PLOS Neglected Tropical Diseases: published May 11, 2026 | https://doi.org/10.1371/journal.pntd.0014250
Metabolomic atlas of dengue virus infection reveals distinct circulating bioactive lipid signatures
PLOS Neglected Tropical Diseases: published May 12, 2026 | https://doi.org/10.1371/journal.pntd.0014327
Transmission potential of Culex and Aedes species for Madariaga virus, a member of the eastern equine encephalitis virus complex
PLOS Neglected Tropical Diseases: published May 12, 2026 | https://doi.org/10.1371/journal.pntd.0013516
Elucidating the causal mechanisms of Taenia solium transmission in humans, pigs and the environment: A global systematic review
PLOS Neglected Tropical Diseases: published May 12, 2026 | https://doi.org/10.1371/journal.pntd.0014281
Paragonimus proliferus Metacercaria-derived antigens mitigate DSS-Induced Ulcerative Colitis via immunomodulation and gut microbiota reconfiguration
PLOS Neglected Tropical Diseases: published May 13, 2026 | https://doi.org/10.1371/journal.pntd.0014340
Cost-effectiveness of soil-transmitted helminthiasis intervention programmes: A scoping review
PLOS Neglected Tropical Diseases: published May 13, 2026 | https://doi.org/10.1371/journal.pntd.0014317
Phlebotomine sand fly fauna characterization and Bartonella bacilliformis DNA detection in Pintomyia (Pifanomyia) robusta at the Ecuador-Peru frontier
PLOS Neglected Tropical Diseases: published May 13, 2026 | https://doi.org/10.1371/journal.pntd.0014288
Evolutionary trends of plague research from 2016 to 2025: A bibliometric analysis
PLOS Neglected Tropical Diseases: published May 13, 2026 | https://doi.org/10.1371/journal.pntd.0014337
Molecular detection and genetic characterisation of a large flood-borne outbreak of human leptospirosis in Jakarta, Indonesia: A retrospective analysis of surveillance data
PLOS Neglected Tropical Diseases: published May 13, 2026 | https://doi.org/10.1371/journal.pntd.0014243
Safety and pharmacokinetics of GSK3494245, a highly selective Leishmaniasis kinetoplastid proteasome inhibitor for the treatment of visceral leishmaniasis: A Phase 1, randomized, single ascending dose escalation study in healthy participants
PLOS Neglected Tropical Diseases: published May 13, 2026 | https://doi.org/10.1371/journal.pntd.0014181
Antigenic divergence of cobra short-chain α-neurotoxins: Implications for regional antivenom effectiveness in Southeast Asia
PLOS Neglected Tropical Diseases: published May 14, 2026 | https://doi.org/10.1371/journal.pntd.0013859
PvGTSeq and PvCRiSP: Two amplicon-based targeted sequencing panels for Plasmodium vivax
PLOS Neglected Tropical Diseases: published May 14, 2026 | https://doi.org/10.1371/journal.pntd.0013663
Human resource challenges in leprosy control: A cross-sectional study in southwest border area of China
PLOS Neglected Tropical Diseases: published May 14, 2026 | https://doi.org/10.1371/journal.pntd.0013209
Natural history and impact of Giardia lamblia on child growth attainment and associated pathway-specific biomarkers in a Nicaraguan birth cohort
PLOS Neglected Tropical Diseases: published May 15, 2026 | https://doi.org/10.1371/journal.pntd.0013734
Decision-making for indoor residual spraying in the post-elimination phase of visceral leishmaniasis in Nepal
PLOS Neglected Tropical Diseases: published May 18, 2026 | https://doi.org/10.1371/journal.pntd.0014355
Interaction effects of physicochemical factors on the growth of Burkholderia pseudomallei in soil microcosms
PLOS Neglected Tropical Diseases: published May 18, 2026 | https://doi.org/10.1371/journal.pntd.0014339
Bridging laboratory and field research: Method adjustments to blood feed field-derived Aedes aegypti
PLOS Neglected Tropical Diseases: published May 18, 2026 | https://doi.org/10.1371/journal.pntd.0013339
Nationwide larval mosquito sampling in Cambodian households: Vector species in anthropogenic breeding sites
PLOS Neglected Tropical Diseases: published May 18, 2026 | https://doi.org/10.1371/journal.pntd.0014342
Spatiotemporal trends of neglected tropical disease hospitalizations in Ecuador over 25-years from 2000 to 2024
PLOS Neglected Tropical Diseases: published May 18, 2026 | https://doi.org/10.1371/journal.pntd.0013688
Strengthening frontline capacity for skin neglected tropical diseases: Findings from a global survey
PLOS Neglected Tropical Diseases: published May 18, 2026 | https://doi.org/10.1371/journal.pntd.0014309
Systematic review of health risk assessment in Africa’s bushmeat trade: Are there any risks assessed?
PLOS Neglected Tropical Diseases: published May 18, 2026 | https://doi.org/10.1371/journal.pntd.0014308
Dengue vaccine acceptability in Peru: A mixed-methods study in two dengue-endemic Peruvian cities
PLOS Neglected Tropical Diseases: published May 18, 2026 | https://doi.org/10.1371/journal.pntd.0013572
Approaches to quantifying acceptability of pharmaceutical interventions for neglected tropical diseases: A scoping review
PLOS Neglected Tropical Diseases: published May 18, 2026 | https://doi.org/10.1371/journal.pntd.0014272
Host–virus association databases as tools for understanding viral spillover at varying scales
PLOS Neglected Tropical Diseases: published May 18, 2026 | https://doi.org/10.1371/journal.pntd.0013343
Effectiveness of community engagement in snakebite prevention and proper first aid practices: A community trial in rural Bangladesh
PLOS Neglected Tropical Diseases: published May 18, 2026 | https://doi.org/10.1371/journal.pntd.0014180
Characterization of the first complete genome sequence of yellow fever virus (YFV) in Sierra Leone: Implications for public health
PLOS Neglected Tropical Diseases: published May 18, 2026 | https://doi.org/10.1371/journal.pntd.0014354
A systematic review comparing the performance of alternative blackfly (Simulium) trapping methods against the standard human landing catch (HLC) for onchocerciasis surveillance
PLOS Neglected Tropical Diseases: published May 18, 2026 | https://doi.org/10.1371/journal.pntd.0014359
Parasite exosomes-derived circulating sja-miR-61 and sja-miR-7-5p as Novel biomarkers for the detection of Schistosoma japonicum infection using TaqMan real-time PCR
PLOS Neglected Tropical Diseases: published May 20, 2026 | https://doi.org/10.1371/journal.pntd.0014368
How rash and eschar came to clinical attention in scrub typhus and Japanese spotted fever
PLOS Neglected Tropical Diseases: published May 20, 2026 | https://doi.org/10.1371/journal.pntd.0014377
Climate change induced complex shifts in snake distributions expose people to snakebite and threaten biodiversity
PLOS Neglected Tropical Diseases: published May 21, 2026 | https://doi.org/10.1371/journal.pntd.0014030
Estimating the potential impact of global research on neglected tropical diseases on population-level indicators of health access, sanitation, and research capacity
PLOS Neglected Tropical Diseases: published May 21, 2026 | https://doi.org/10.1371/journal.pntd.0014343
Local heterogeneity in Lassa fever serology in rural Nigeria: Implications for vaccine trial site selection
PLOS Neglected Tropical Diseases: published May 21, 2026 | https://doi.org/10.1371/journal.pntd.0014379
A multicenter hospital-based analysis of cystic Echinococcosis in Afghanistan: Filling a National data gap
PLOS Neglected Tropical Diseases: published May 21, 2026 | https://doi.org/10.1371/journal.pntd.0014357
The need for balanced dengue vaccine protection: Insights from Thai surveillance data on four serotypes
PLOS Neglected Tropical Diseases: published May 22, 2026 | https://doi.org/10.1371/journal.pntd.0014093
The cross-city mobility patterns and incubation period of the early-stage chikungunya fever outbreak in Guangdong Province, China, in 2025
PLOS Neglected Tropical Diseases: published May 22, 2026 | https://doi.org/10.1371/journal.pntd.0014360
The impact of elevation and population density on dengue incidence and force of infection across the Philippines: Implications for climate-adapted surveillance
PLOS Neglected Tropical Diseases: published May 26, 2026 | https://doi.org/10.1371/journal.pntd.0014356
Bothrops jararaca snake venom: A reappraisal of its coagulant activity in humans, mice, and rats
PLOS Neglected Tropical Diseases: published May 26, 2026 | https://doi.org/10.1371/journal.pntd.0014335
Monoclonal antibody-based immunohistochemistry reveals residual Taenia solium antigens in calcified granulomas from pigs with neurocysticercosis
PLOS Neglected Tropical Diseases: published May 26, 2026 | https://doi.org/10.1371/journal.pntd.0014329
Climate change and Plasmodium vivax Malaria Risk in Brazil: Developing adaptive tool for Brazilian Municipalities
PLOS Neglected Tropical Diseases: published May 26, 2026 | https://doi.org/10.1371/journal.pntd.0014298
The atypical dual-specificity protein phosphatase (DUSP)/kinatase of Leishmania infantum modulates infectivity, oxidative stress response and antimonial resistance
PLOS Neglected Tropical Diseases: published May 26, 2026 | https://doi.org/10.1371/journal.pntd.0014330
Burden and clinical impact of ‘neglected’ transfusion-transmitted infections in Cameroon: A systematic review and meta-analysis
PLOS Neglected Tropical Diseases: published May 26, 2026 | https://doi.org/10.1371/journal.pntd.0014378
Expanded molecular evidence of soil-transmitted helminth and Schistosoma spp. infections in Myanmar schoolchildren: A qPCR update
PLOS Neglected Tropical Diseases: published May 26, 2026 | https://doi.org/10.1371/journal.pntd.0014384
Discovery of two novel mutations, R52H and N868D, in the voltage-gated sodium channel of Aedes aegypti associated with pyrethroid resistance
PLOS Neglected Tropical Diseases: published May 26, 2026 | https://doi.org/10.1371/journal.pntd.0014393
High-resolution automated mapping of potential Aedes larval container habitats using drone imagery and supervised machine learning in Dar es Salaam, Tanzania
PLOS Neglected Tropical Diseases: published May 26, 2026 | https://doi.org/10.1371/journal.pntd.0014361
Global burden, projections, and causal factors of maternal sepsis and other maternal infections: A comprehensive epidemiological and mendelian randomization study
PLOS Neglected Tropical Diseases: published May 27, 2026 | https://doi.org/10.1371/journal.pntd.0014374
Clinical outcomes associated with schistosome infection and alcohol use: A systematic scoping review
PLOS Neglected Tropical Diseases: published May 27, 2026 | https://doi.org/10.1371/journal.pntd.0014371
Interactions between mosquito genetic background and Wolbachia strain affect dengue virus blocking and fitness in South American populations of Aedes aegypti
PLOS Neglected Tropical Diseases: published May 27, 2026 | https://doi.org/10.1371/journal.pntd.0014403
Feasibility study of an AI-powered mobile app to support cutaneous leishmaniasis diagnosis in the Brazilian Amazon
PLOS Neglected Tropical Diseases: published May 27, 2026 | https://doi.org/10.1371/journal.pntd.0014313
Crimean–congo haemorrhagic fever virus circulates within broad ecological networks of ticks and vertebrates
PLOS Neglected Tropical Diseases: published May 27, 2026 | https://doi.org/10.1371/journal.pntd.0013783
Unravelling the distribution of vectors of major vector-borne diseases in Koshi Province of Nepal: A concern of expansion in diverse geo-ecological and climatic regions
PLOS Neglected Tropical Diseases: published May 29, 2026 | https://doi.org/10.1371/journal.pntd.0013188
Leishmania major virulence attenuation in vitro: An old conundrum revisited in the omics era
PLOS Neglected Tropical Diseases: published May 29, 2026 | https://doi.org/10.1371/journal.pntd.0014387
Spatiotemporal dynamics and serosurveillance landscape of brucellosis at the human-animal interface in the Chinese Southwest: A retrospective study
PLOS Neglected Tropical Diseases: published May 29, 2026 | https://doi.org/10.1371/journal.pntd.0014358
Clinical characteristics, treatment outcomes, and predictors of early mortality in Vibrio vulnificus infection in Eastern Thailand: A 6.5-year multicenter cohort study
PLOS Neglected Tropical Diseases: published May 29, 2026 | https://doi.org/10.1371/journal.pntd.0014353
Corrections
Correction: Orientia tsutsugamushi Stimulates an Original Gene Expression Program in Monocytes: Relationship with Gene Expression in Patients with Scrub Typhus
PLOS Neglected Tropical Diseases: published May 4, 2026 | https://doi.org/10.1371/journal.pntd.0014279
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Correction: Molecular and MALDI-TOF identification of ticks and tick-associated bacteria in Mali
PLOS Neglected Tropical Diseases: published May 12, 2026 | https://doi.org/10.1371/journal.pntd.0014311
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Correction: Community participation and technological innovation: Baseline qualitative insights to inform a five-year cohort on drone-based dengue surveillance in Malaysia
PLOS Neglected Tropical Diseases: published May 13, 2026 | https://doi.org/10.1371/journal.pntd.0014316
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Correction: Establishing an external quality assurance scheme for the detection of Orientia tsutsugamushi IgM in clinical samples: Strengthening quality control of scrub typhus diagnosis in Indian laboratories
PLOS Neglected Tropical Diseases: published May 18, 2026 | https://doi.org/10.1371/journal.pntd.0014324
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Correction: Transcriptomic and ultrastructural responses to Amiodarone–Itraconazole in naturally benznidazole-resistant and -susceptible Trypanosoma cruzi strains
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Retractions
Retraction: Body lice of homeless people reveal the presence of several emerging bacterial pathogens in northern Algeria
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Retraction: Tick-borne rickettsioses, neglected emerging diseases in rural senegal
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Editorial Notes
Editorial Note: Multiple Pathogens Including Potential New Species in Tick Vectors in Côte d’Ivoire
PLOS Neglected Tropical Diseases: published May 20, 2026 | https://doi.org/10.1371/journal.pntd.0014341
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Editorial Note: Detection of relapsing fever Borrelia spp., Bartonella spp. and Anaplasmataceae bacteria in argasid ticks in Algeria
PLOS Neglected Tropical Diseases: published May 22, 2026 | https://doi.org/10.1371/journal.pntd.0014351