Plasmodium vivax is a widespread cause of malaria in Mauritania, particularly in the Saharan zone. Analysis of a genome-wide panel of single nucleotide polymorphisms reveals the Mauritanian P. vivax population to be genetically diverse and divergent from parasites elsewhere. The parasites apparently undergo frequent recombination, there is no indication of local epidemic population structure, and only a few infections have closely related genotypes. Drug resistance alleles are absent or very rare, suggesting that most infections have been untreated historically. The molecular epidemiology indicates long-standing endemic transmission of this neglected parasite that requires special attention for control. Ba, et al. (2020)
Image Credit: David Conway
Editorial
COVID-19 in the Americas and the erosion of human rights for the poor
PLOS Neglected Tropical Diseases: published December 18, 2020 | https://doi.org/10.1371/journal.pntd.0008954
Viewpoints
Time for a diagnostic sea-change: Rethinking neglected tropical disease diagnostics to achieve elimination
PLOS Neglected Tropical Diseases: published December 31, 2020 | https://doi.org/10.1371/journal.pntd.0008933
Mild manifestations of COVID-19 in healthcare workers
PLOS Neglected Tropical Diseases: published December 22, 2020 | https://doi.org/10.1371/journal.pntd.0008950
COVID-19 epidemic in the US—A gateway to screen for tuberculosis, HIV, viral hepatitides, Chagas disease, and other neglected tropical diseases among Hispanics
PLOS Neglected Tropical Diseases: published December 18, 2020 | https://doi.org/10.1371/journal.pntd.0008953
Symposiums
An unhealing wound and subcutaneous nodules due to Sporothrix globosa after a cat bite
PLOS Neglected Tropical Diseases: published December 3, 2020 | https://doi.org/10.1371/journal.pntd.0008859
Actinomycetoma with systemic features: A warning sign for immunosuppression?
PLOS Neglected Tropical Diseases: published December 3, 2020 | https://doi.org/10.1371/journal.pntd.0008865
Challenges in establishing telehealth care during the COVID-19 pandemic in a neglected HTLV-1-infected population in northeastern Brazil
PLOS Neglected Tropical Diseases: published December 31, 2020 | https://doi.org/10.1371/journal.pntd.0008922
Reviews
Plasmodium knowlesi infecting humans in Southeast Asia: What’s next?
PLOS Neglected Tropical Diseases: published December 31, 2020 | https://doi.org/10.1371/journal.pntd.0008900
Pathophysiology of ocular toxoplasmosis: Facts and open questions
PLOS Neglected Tropical Diseases: published December 31, 2020 | https://doi.org/10.1371/journal.pntd.0008905
Research Articles
Helminth infections among rural schoolchildren in Southern Ethiopia: A cross-sectional multilevel and zero-inflated regression model
PLOS Neglected Tropical Diseases: published December 22, 2020 | https://doi.org/10.1371/journal.pntd.0008002
Zika and dengue but not chikungunya are associated with Guillain-Barré syndrome in Mexico: A case-control study
PLOS Neglected Tropical Diseases: published December 17, 2020 | https://doi.org/10.1371/journal.pntd.0008032
Post-intervention epidemiology of STH in Bangladesh: Data to sustain the gains
PLOS Neglected Tropical Diseases: published December 7, 2020 | https://doi.org/10.1371/journal.pntd.0008597
Risk mapping of scrub typhus infections in Qingdao city, China
PLOS Neglected Tropical Diseases: published December 2, 2020 | https://doi.org/10.1371/journal.pntd.0008757
Community perspectives on scabies, impetigo and mass drug administration in Fiji: A qualitative study
PLOS Neglected Tropical Diseases: published December 4, 2020 | https://doi.org/10.1371/journal.pntd.0008825
Cost of a new method of active screening for human African trypanosomiasis in the Democratic Republic of the Congo
PLOS Neglected Tropical Diseases: published December 14, 2020 | https://doi.org/10.1371/journal.pntd.0008832
Quantitative lipidomic analysis of Ascaris suum
PLOS Neglected Tropical Diseases: published December 2, 2020 | https://doi.org/10.1371/journal.pntd.0008848
Diagnostic accuracy of an in-house Scrub Typhus enzyme linked immunoassay for the detection of IgM and IgG antibodies in Laos
PLOS Neglected Tropical Diseases: published December 7, 2020 | https://doi.org/10.1371/journal.pntd.0008858
Schistosoma haematobium infection is associated with alterations in energy and purine-related metabolism in preschool-aged children
PLOS Neglected Tropical Diseases: published December 14, 2020 | https://doi.org/10.1371/journal.pntd.0008866
Vertebrate-Aedes aegypti and Culex quinquefasciatus (Diptera)-arbovirus transmission networks: Non-human feeding revealed by meta-barcoding and next-generation sequencing
PLOS Neglected Tropical Diseases: published December 31, 2020 | https://doi.org/10.1371/journal.pntd.0008867
Alteration in the Culex pipiens transcriptome reveals diverse mechanisms of the mosquito immune system implicated upon Rift Valley fever phlebovirus exposure
PLOS Neglected Tropical Diseases: published December 10, 2020 | https://doi.org/10.1371/journal.pntd.0008870
Targeting female flight for genetic control of mosquitoes
PLOS Neglected Tropical Diseases: published December 3, 2020 | https://doi.org/10.1371/journal.pntd.0008876
Achievements and challenges of lymphatic filariasis elimination in Sierra Leone
PLOS Neglected Tropical Diseases: published December 28, 2020 | https://doi.org/10.1371/journal.pntd.0008877
Spatiotemporal analysis of mycolactone distribution in vivo reveals partial diffusion in the central nervous system
PLOS Neglected Tropical Diseases: published December 2, 2020 | https://doi.org/10.1371/journal.pntd.0008878
Co-infection of Dengue, Zika and Chikungunya in a group of pregnant women from Tuxtla Gutiérrez, Chiapas: Preliminary data. 2019
PLOS Neglected Tropical Diseases: published December 21, 2020 | https://doi.org/10.1371/journal.pntd.0008880
Effect of repeated epilation for minor trachomatous trichiasis on lash burden, phenotype and surgical management willingness: A cohort study
PLOS Neglected Tropical Diseases: published December 14, 2020 | https://doi.org/10.1371/journal.pntd.0008882
Polymorphisms in mitochondrial ribosomal protein S5 (MRPS5) are associated with leprosy risk in Chinese
PLOS Neglected Tropical Diseases: published December 23, 2020 | https://doi.org/10.1371/journal.pntd.0008883
Population pharmacokinetics of ivermectin for the treatment of scabies in Indigenous Australian children
PLOS Neglected Tropical Diseases: published December 7, 2020 | https://doi.org/10.1371/journal.pntd.0008886
Hospital admissions for skin and soft tissue infections in a population with endemic scabies: A prospective study in Fiji, 2018–2019
PLOS Neglected Tropical Diseases: published December 9, 2020 | https://doi.org/10.1371/journal.pntd.0008887
Cell membrane components of Brucella melitensis play important roles in the resistance of low-level rifampicin
PLOS Neglected Tropical Diseases: published December 29, 2020 | https://doi.org/10.1371/journal.pntd.0008888
miRNAs may play a major role in the control of gene expression in key pathobiological processes in Chagas disease cardiomyopathy
PLOS Neglected Tropical Diseases: published December 22, 2020 | https://doi.org/10.1371/journal.pntd.0008889
Diagnostic differentiation of Zika and dengue virus exposure by analyzing T cell receptor sequences from peripheral blood of infected HLA-A2 transgenic mice
PLOS Neglected Tropical Diseases: published December 3, 2020 | https://doi.org/10.1371/journal.pntd.0008896
The development of a novel diagnostic PCR for Madurella mycetomatis using a comparative genome approach
PLOS Neglected Tropical Diseases: published December 16, 2020 | https://doi.org/10.1371/journal.pntd.0008897
Experimental Lagos bat virus infection in straw-colored fruit bats: A suitable model for bat rabies in a natural reservoir species
PLOS Neglected Tropical Diseases: published December 15, 2020 | https://doi.org/10.1371/journal.pntd.0008898
Genetic and toxinological divergence among populations of Tityus trivittatus Kraepelin, 1898 (Scorpiones: Buthidae) inhabiting Paraguay and Argentina
PLOS Neglected Tropical Diseases: published December 14, 2020 | https://doi.org/10.1371/journal.pntd.0008899
A scabies outbreak in the North East Region of Ghana: The necessity for prompt intervention
PLOS Neglected Tropical Diseases: published December 22, 2020 | https://doi.org/10.1371/journal.pntd.0008902
Delimiting cryptic morphological variation among human malaria vector species using convolutional neural networks
PLOS Neglected Tropical Diseases: published December 17, 2020 | https://doi.org/10.1371/journal.pntd.0008904
Epidemiology of soil-transmitted helminth infections in Semarang, Central Java, Indonesia
PLOS Neglected Tropical Diseases: published December 28, 2020 | https://doi.org/10.1371/journal.pntd.0008907
Risk assessment and evaluation of China’s policy to prevent COVID-19 cases imported by plane
PLOS Neglected Tropical Diseases: published December 7, 2020 | https://doi.org/10.1371/journal.pntd.0008908
Loss of natural resistance to schistosome in T cell deficient rat
PLOS Neglected Tropical Diseases: published December 21, 2020 | https://doi.org/10.1371/journal.pntd.0008909
Adenovirus vectored IFN-α protects mice from lethal challenge of Chikungunya virus infection
PLOS Neglected Tropical Diseases: published December 3, 2020 | https://doi.org/10.1371/journal.pntd.0008910
Venomous snakebites: Rapid action saves lives—A multifaceted community education programme increases awareness about snakes and snakebites among the rural population of Tamil Nadu, India
PLOS Neglected Tropical Diseases: published December 31, 2020 | https://doi.org/10.1371/journal.pntd.0008911
Potential strategies for strengthening surveillance of lymphatic filariasis in American Samoa after mass drug administration: Reducing ‘number needed to test’ by targeting older age groups, hotspots, and household members of infected persons
PLOS Neglected Tropical Diseases: published December 28, 2020 | https://doi.org/10.1371/journal.pntd.0008916
Leprosy in a prison population: A new active search strategy and a prospective clinical analysis
PLOS Neglected Tropical Diseases: published December 10, 2020 | https://doi.org/10.1371/journal.pntd.0008917
Seroprevalence and associated risk factors of Dengue fever in Kassala state, eastern Sudan
PLOS Neglected Tropical Diseases: published December 9, 2020 | https://doi.org/10.1371/journal.pntd.0008918
Antischistosomal, antionchocercal and antitrypanosomal potentials of some Ghanaian traditional medicines and their constituents
PLOS Neglected Tropical Diseases: published December 31, 2020 | https://doi.org/10.1371/journal.pntd.0008919
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Immunohistological detection of small particles of Echinococcus multilocularis and Echinococcus granulosus in lymph nodes is associated with enlarged lymph nodes in alveolar and cystic echinococcosis
PLOS Neglected Tropical Diseases: published December 28, 2020 | https://doi.org/10.1371/journal.pntd.0008921
Enhancing fine-grained intra-urban dengue forecasting by integrating spatial interactions of human movements between urban regions
PLOS Neglected Tropical Diseases: published December 21, 2020 | https://doi.org/10.1371/journal.pntd.0008924
Lymphatic filariasis epidemiology in Samoa in 2018: Geographic clustering and higher antigen prevalence in older age groups
PLOS Neglected Tropical Diseases: published December 21, 2020 | https://doi.org/10.1371/journal.pntd.0008927
Halogenated tryptophan derivatives disrupt essential transamination mechanisms in bloodstream form Trypanosoma brucei
PLOS Neglected Tropical Diseases: published December 4, 2020 | https://doi.org/10.1371/journal.pntd.0008928
Corallopyronin A for short-course anti-wolbachial, macrofilaricidal treatment of filarial infections
PLOS Neglected Tropical Diseases: published December 7, 2020 | https://doi.org/10.1371/journal.pntd.0008930
Hepatitis C (HCV) therapy for HCV mono-infected and HIV-HCV co-infected individuals living in Nepal
PLOS Neglected Tropical Diseases: published December 16, 2020 | https://doi.org/10.1371/journal.pntd.0008931
Genetic diversity of Trypanosoma cruzi parasites infecting dogs in southern Louisiana sheds light on parasite transmission cycles and serological diagnostic performance
PLOS Neglected Tropical Diseases: published December 17, 2020 | https://doi.org/10.1371/journal.pntd.0008932
An investig-ation into the epidemiology of chikungunya virus across neglected regions of Indonesia
PLOS Neglected Tropical Diseases: published December 21, 2020 | https://doi.org/10.1371/journal.pntd.0008934
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Snakebite associated thrombotic microangiopathy: a systematic review of clinical features, outcomes, and evidence for interventions including plasmapheresis
PLOS Neglected Tropical Diseases: published December 8, 2020 | https://doi.org/10.1371/journal.pntd.0008936
Meningitis patients with Angiostrongylus cantonensis may present without eosinophilia in the cerebrospinal fluid in northern Vietnam
PLOS Neglected Tropical Diseases: published December 22, 2020 | https://doi.org/10.1371/journal.pntd.0008937
Prevalence, risk factors and health consequences of soil-transmitted helminth infection on the Bijagos Islands, Guinea Bissau: A community-wide cross-sectional study
PLOS Neglected Tropical Diseases: published December 16, 2020 | https://doi.org/10.1371/journal.pntd.0008938
Prediction of hot spot areas of hemorrhagic fever with renal syndrome in Hunan Province based on an information quantity model and logistical regression model
PLOS Neglected Tropical Diseases: published December 21, 2020 | https://doi.org/10.1371/journal.pntd.0008939
Using host traits to predict reservoir host species of rabies virus
PLOS Neglected Tropical Diseases: published December 8, 2020 | https://doi.org/10.1371/journal.pntd.0008940
Vector competence of Aedes aegypti from Havana, Cuba, for dengue virus type 1, chikungunya, and Zika viruses
PLOS Neglected Tropical Diseases: published December 3, 2020 | https://doi.org/10.1371/journal.pntd.0008941
Recombinant Rift Valley fever viruses encoding bluetongue virus (BTV) antigens: Immunity and efficacy studies upon a BTV-4 challenge
PLOS Neglected Tropical Diseases: published December 4, 2020 | https://doi.org/10.1371/journal.pntd.0008942
The prevalence of scabies in Monrovia, Liberia: A population-based survey
PLOS Neglected Tropical Diseases: published December 7, 2020 | https://doi.org/10.1371/journal.pntd.0008943
Potential risk factors associated with seropositivity for Toxoplasma gondii among pregnant women and HIV infected individuals in Ethiopia: A systematic review and meta-analysis
PLOS Neglected Tropical Diseases: published December 15, 2020 | https://doi.org/10.1371/journal.pntd.0008944
Multi-locus genotyping reveals established endemicity of a geographically distinct Plasmodium vivax population in Mauritania, West Africa
PLOS Neglected Tropical Diseases: published December 16, 2020 | https://doi.org/10.1371/journal.pntd.0008945
Effects of land use, habitat characteristics, and small mammal community composition on Leptospira prevalence in northeast Madagascar
PLOS Neglected Tropical Diseases: published December 31, 2020 | https://doi.org/10.1371/journal.pntd.0008946
Potential of Artesunate in the treatment of visceral leishmaniasis in dogs naturally infected by Leishmania infantum: Efficacy evidence from a randomized field trial
PLOS Neglected Tropical Diseases: published December 18, 2020 | https://doi.org/10.1371/journal.pntd.0008947
Application of the GARC Data Logger—a custom-developed data collection device—to capture and monitor mass dog vaccination campaigns in Namibia
PLOS Neglected Tropical Diseases: published December 28, 2020 | https://doi.org/10.1371/journal.pntd.0008948
Epidemic risk of arboviral diseases: Determining the habitats, spatial-temporal distribution, and abundance of immature Aedes aegypti in the Urban and Rural areas of Zanzibar, Tanzania
PLOS Neglected Tropical Diseases: published December 7, 2020 | https://doi.org/10.1371/journal.pntd.0008949
Dysregulation of hepatic microRNA expression in C57BL/6 mice affected by excretory-secretory products of Fasciola gigantica
PLOS Neglected Tropical Diseases: published December 17, 2020 | https://doi.org/10.1371/journal.pntd.0008951
Sodium-bile acid co-transporter is crucial for survival of a carcinogenic liver fluke Clonorchis sinensis in the bile
PLOS Neglected Tropical Diseases: published December 7, 2020 | https://doi.org/10.1371/journal.pntd.0008952
Presence of the knockdown resistance (kdr) mutations in the head lice (Pediculus humanus capitis) collected from primary school children of Thailand
PLOS Neglected Tropical Diseases: published December 16, 2020 | https://doi.org/10.1371/journal.pntd.0008955
Improving dog bite victim survey and estimation of annual human deaths due to suspected rabies cases in three selected Liberian cities and environs, 2008–2017
PLOS Neglected Tropical Diseases: published December 28, 2020 | https://doi.org/10.1371/journal.pntd.0008957
Identification of chironomid species as natural reservoirs of toxigenic Vibrio cholerae strains with pandemic potential
PLOS Neglected Tropical Diseases: published December 23, 2020 | https://doi.org/10.1371/journal.pntd.0008959
Assessing the risk of dengue severity using demographic information and laboratory test results with machine learning
PLOS Neglected Tropical Diseases: published December 23, 2020 | https://doi.org/10.1371/journal.pntd.0008960
Understanding COVID-19 vaccine demand and hesitancy: A nationwide online survey in China
PLOS Neglected Tropical Diseases: published December 17, 2020 | https://doi.org/10.1371/journal.pntd.0008961
Population genomics of Plasmodium vivax in Panama to assess the risk of case importation on malaria elimination
PLOS Neglected Tropical Diseases: published December 14, 2020 | https://doi.org/10.1371/journal.pntd.0008962
Diagnostic accuracy of direct agglutination test, rK39 ELISA and six rapid diagnostic tests among visceral leishmaniasis patients with and without HIV coinfection in Ethiopia
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Taenia larvae possess distinct acetylcholinesterase profiles with implications for host cholinergic signalling
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Molecular signatures of sexual communication in the phlebotomine sand flies
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CD8low T cells expanded following acute Trypanosoma cruzi infection and benznidazole treatment are a relevant subset of IFN-γ producers
PLOS Neglected Tropical Diseases: published December 21, 2020 | https://doi.org/10.1371/journal.pntd.0008969
CRISPR/Cas9 knockout of female-biased genes AeAct-4 or myo-fem in Ae. aegypti results in a flightless phenotype in female, but not male mosquitoes
PLOS Neglected Tropical Diseases: published December 18, 2020 | https://doi.org/10.1371/journal.pntd.0008971
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Formal Comment
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