Brugia malayi microfilariae found in the bloodstream of the infected human host are surrounded by a translucent sheath derived from the embryonic egg shell. The sheath appears to protect the microfilariae from interaction with the immune system. Treatment with calcium chloride results in loss of the sheath. The image shows the luminescence of an exsheathed microfilariae under light microscopy. Schroeder et al.
Image Credit: Rachel A. Lawrence
Editorial
Russian–United States vaccine science diplomacy: Preserving the legacy
PLOS Neglected Tropical Diseases: published May 25, 2017 | https://doi.org/10.1371/journal.pntd.0005320
Viewpoints
NTD policy priorities: Science, values, and agenda setting
PLOS Neglected Tropical Diseases: published May 18, 2017 | https://doi.org/10.1371/journal.pntd.0005431
The risk of transmission of a viral haemorrhagic fever infection in a United Kingdom laboratory
PLOS Neglected Tropical Diseases: published May 18, 2017 | https://doi.org/10.1371/journal.pntd.0005358
Policy Platform
Global practices in regard to implementation of preventive measures for leprosy
PLOS Neglected Tropical Diseases: published May 4, 2017 | https://doi.org/10.1371/journal.pntd.0005399
From Innovation to Application
Preheating of urine improves the specificity of urinary cryptococcal antigen testing using the lateral flow assay
PLOS Neglected Tropical Diseases: published May 11, 2017 | https://doi.org/10.1371/journal.pntd.0005304
Symposiums
Successful treatment of 2 imported cases of Mansonella perstans infection
PLOS Neglected Tropical Diseases: published May 25, 2017 | https://doi.org/10.1371/journal.pntd.0005452
Visceral leishmaniasis complicating idiopathic CD4+ T-cell lymphocytopenia: 2 case reports
PLOS Neglected Tropical Diseases: published May 11, 2017 | https://doi.org/10.1371/journal.pntd.0005412
“Locked in a cage”—A case of dengue virus 4 encephalitis
PLOS Neglected Tropical Diseases: published May 4, 2017 | https://doi.org/10.1371/journal.pntd.0005369
Review
Melioidosis: Clinical impact and public health threat in the tropics
PLOS Neglected Tropical Diseases: published May 11, 2017 | https://doi.org/10.1371/journal.pntd.0004738
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Research Articles
Different features of Vδ2 T and NK cells in fatal and non-fatal human Ebola infections
PLOS Neglected Tropical Diseases: published May 30, 2017 | https://doi.org/10.1371/journal.pntd.0005645
Vaccination with a Leishmania infantum HSP70-II null mutant confers long-term protective immunity against Leishmania major infection in two mice models
PLOS Neglected Tropical Diseases: published May 30, 2017 | https://doi.org/10.1371/journal.pntd.0005644
Fine-scale variation in microclimate across an urban landscape shapes variation in mosquito population dynamics and the potential of Aedes albopictus to transmit arboviral disease
PLOS Neglected Tropical Diseases: published May 30, 2017 | https://doi.org/10.1371/journal.pntd.0005640
Safety and efficacy of short course combination regimens with AmBisome, miltefosine and paromomycin for the treatment of visceral leishmaniasis (VL) in Bangladesh
PLOS Neglected Tropical Diseases: published May 30, 2017 | https://doi.org/10.1371/journal.pntd.0005635
Epitope mapping of recombinant Leishmania donovani virulence factor A2 (recLdVFA2) and canine leishmaniasis diagnosis using a derived synthetic bi-epitope
PLOS Neglected Tropical Diseases: published May 30, 2017 | https://doi.org/10.1371/journal.pntd.0005562
Optimising cluster survey design for planning schistosomiasis preventive chemotherapy
PLOS Neglected Tropical Diseases: published May 26, 2017 | https://doi.org/10.1371/journal.pntd.0005599
Albendazole increases the inflammatory response and the amount of Em2-positive small particles of Echinococcus multilocularis (spems) in human hepatic alveolar echinococcosis lesions
PLOS Neglected Tropical Diseases: published May 25, 2017 | https://doi.org/10.1371/journal.pntd.0005636
Hookworm infection is associated with decreased CD4+ T cell counts in HIV-infected adult Ugandans
PLOS Neglected Tropical Diseases: published May 25, 2017 | https://doi.org/10.1371/journal.pntd.0005634
Unravelling the rate of action of hits in the Leishmania donovani box using standard drugs amphotericin B and miltefosine
PLOS Neglected Tropical Diseases: published May 25, 2017 | https://doi.org/10.1371/journal.pntd.0005629
Health beliefs of school-age rural children in podoconiosis-affected families: A qualitative study in Southern Ethiopia
PLOS Neglected Tropical Diseases: published May 25, 2017 | https://doi.org/10.1371/journal.pntd.0005564
Clonorchis sinensis antigens alter hepatic macrophage polarization in vitro and in vivo
PLOS Neglected Tropical Diseases: published May 24, 2017 | https://doi.org/10.1371/journal.pntd.0005614
Using G6PD tests to enable the safe treatment of Plasmodium vivax infections with primaquine on the Thailand-Myanmar border: A cost-effectiveness analysis
PLOS Neglected Tropical Diseases: published May 24, 2017 | https://doi.org/10.1371/journal.pntd.0005602
“We do not bury dead livestock like human beings”: Community behaviors and risk of Rift Valley Fever virus infection in Baringo County, Kenya
PLOS Neglected Tropical Diseases: published May 24, 2017 | https://doi.org/10.1371/journal.pntd.0005582
The impact of health promotion on trachoma knowledge, attitudes and practice (KAP) of staff in three work settings in remote Indigenous communities in the Northern Territory
PLOS Neglected Tropical Diseases: published May 24, 2017 | https://doi.org/10.1371/journal.pntd.0005503
MiR-277/4989 regulate transcriptional landscape during juvenile to adult transition in the parasitic helminth Schistosoma mansoni
PLOS Neglected Tropical Diseases: published May 23, 2017 | https://doi.org/10.1371/journal.pntd.0005559
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Highly conserved type 1 pili promote enterotoxigenic E. coli pathogen-host interactions
PLOS Neglected Tropical Diseases: published May 22, 2017 | https://doi.org/10.1371/journal.pntd.0005586
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PLOS Neglected Tropical Diseases: published May 22, 2017 | https://doi.org/10.1371/journal.pntd.0005585
Dengue in Bali: Clinical characteristics and genetic diversity of circulating dengue viruses
PLOS Neglected Tropical Diseases: published May 22, 2017 | https://doi.org/10.1371/journal.pntd.0005483
Measuring changes in transmission of neglected tropical diseases, malaria, and enteric pathogens from quantitative antibody levels
PLOS Neglected Tropical Diseases: published May 19, 2017 | https://doi.org/10.1371/journal.pntd.0005616
Detecting infection hotspots: Modeling the surveillance challenge for elimination of lymphatic filariasis
PLOS Neglected Tropical Diseases: published May 19, 2017 | https://doi.org/10.1371/journal.pntd.0005610
Single-sex infection with female Schistosoma mansoni cercariae mitigates hepatic fibrosis after secondary infection
PLOS Neglected Tropical Diseases: published May 19, 2017 | https://doi.org/10.1371/journal.pntd.0005595
The phylogeography of Myotis bat-associated rabies viruses across Canada
PLOS Neglected Tropical Diseases: published May 19, 2017 | https://doi.org/10.1371/journal.pntd.0005541
wMel limits zika and chikungunya virus infection in a Singapore Wolbachia-introgressed Ae. aegypti strain, wMel-Sg
PLOS Neglected Tropical Diseases: published May 19, 2017 | https://doi.org/10.1371/journal.pntd.0005496
Northern range expansion of the Asian tiger mosquito (Aedes albopictus): Analysis of mosquito data from Connecticut, USA
PLOS Neglected Tropical Diseases: published May 18, 2017 | https://doi.org/10.1371/journal.pntd.0005623
Mortality among blood donors seropositive and seronegative for Chagas disease (1996–2000) in São Paulo, Brazil: A death certificate linkage study
PLOS Neglected Tropical Diseases: published May 18, 2017 | https://doi.org/10.1371/journal.pntd.0005542
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Neotropical bats that co-habit with humans function as dead-end hosts for dengue virus
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Development of a movement-based in vitro screening assay for the identification of new anti-cestodal compounds
PLOS Neglected Tropical Diseases: published May 17, 2017 | https://doi.org/10.1371/journal.pntd.0005618
Outdoor spatial spraying against dengue: A false sense of security among inhabitants of Hermosillo, Mexico
PLOS Neglected Tropical Diseases: published May 17, 2017 | https://doi.org/10.1371/journal.pntd.0005611
Dose of antivenom for the treatment of snakebite with neurotoxic envenoming: Evidence from a randomised controlled trial in Nepal
PLOS Neglected Tropical Diseases: published May 16, 2017 | https://doi.org/10.1371/journal.pntd.0005612
The Biomphalaria glabrata DNA methylation machinery displays spatial tissue expression, is differentially active in distinct snail populations and is modulated by interactions with Schistosoma mansoni
PLOS Neglected Tropical Diseases: published May 16, 2017 | https://doi.org/10.1371/journal.pntd.0005246
Rapid deployment of a mobile biosafety level-3 laboratory in Sierra Leone during the 2014 Ebola virus epidemic
PLOS Neglected Tropical Diseases: published May 15, 2017 | https://doi.org/10.1371/journal.pntd.0005622
Combined treatment of miltefosine and paromomycin delays the onset of experimental drug resistance in Leishmania infantum
PLOS Neglected Tropical Diseases: published May 15, 2017 | https://doi.org/10.1371/journal.pntd.0005620
Strongyloides seroprevalence before and after an ivermectin mass drug administration in a remote Australian Aboriginal community
PLOS Neglected Tropical Diseases: published May 15, 2017 | https://doi.org/10.1371/journal.pntd.0005607
Structurally optimized analogs of the retrograde trafficking inhibitor Retro-2cycl limit Leishmania infections
PLOS Neglected Tropical Diseases: published May 15, 2017 | https://doi.org/10.1371/journal.pntd.0005556
Dissecting the human serum antibody response to secondary dengue virus infections
PLOS Neglected Tropical Diseases: published May 15, 2017 | https://doi.org/10.1371/journal.pntd.0005554
Awareness and attitudes towards anthrax and meat consumption practices among affected communities in Zambia: A mixed methods approach
PLOS Neglected Tropical Diseases: published May 12, 2017 | https://doi.org/10.1371/journal.pntd.0005580
A third generation vaccine for human visceral leishmaniasis and post kala azar dermal leishmaniasis: First-in-human trial of ChAd63-KH
PLOS Neglected Tropical Diseases: published May 12, 2017 | https://doi.org/10.1371/journal.pntd.0005527
Improving drug delivery strategies for lymphatic filariasis elimination in urban areas in Ghana
PLOS Neglected Tropical Diseases: published May 11, 2017 | https://doi.org/10.1371/journal.pntd.0005619
Ileus in children presenting with diarrhea and severe acute malnutrition: A chart review
PLOS Neglected Tropical Diseases: published May 11, 2017 | https://doi.org/10.1371/journal.pntd.0005603
The mitochondrial SIR2 related protein 2 (SIR2RP2) impacts Leishmania donovani growth and infectivity
PLOS Neglected Tropical Diseases: published May 11, 2017 | https://doi.org/10.1371/journal.pntd.0005590
Time trend of neurocysticercosis in children with seizures in a tertiary hospital of western Nepal
PLOS Neglected Tropical Diseases: published May 10, 2017 | https://doi.org/10.1371/journal.pntd.0005605
Functional and phenotypic evaluation of eosinophils from patients with the acute form of paracoccidioidomycosis
PLOS Neglected Tropical Diseases: published May 10, 2017 | https://doi.org/10.1371/journal.pntd.0005601
An environmental assessment and risk map of Ascaris lumbricoides and Necator americanus distributions in Manufahi District, Timor-Leste
PLOS Neglected Tropical Diseases: published May 10, 2017 | https://doi.org/10.1371/journal.pntd.0005565
Haemophilus ducreyi DNA is detectable on the skin of asymptomatic children, flies and fomites in villages of Papua New Guinea
PLOS Neglected Tropical Diseases: published May 10, 2017 | https://doi.org/10.1371/journal.pntd.0004958
Migratory phase of Litomosoides sigmodontis filarial infective larvae is associated with pathology and transient increase of S100A9 expressing neutrophils in the lung
PLOS Neglected Tropical Diseases: published May 9, 2017 | https://doi.org/10.1371/journal.pntd.0005596
Zika virus-like particle (VLP) based vaccine
PLOS Neglected Tropical Diseases: published May 8, 2017 | https://doi.org/10.1371/journal.pntd.0005608
Abnormal neurobehaviour and impaired memory function as a consequence of Toxocara canis- as well as Toxocara cati-induced neurotoxocarosis
PLOS Neglected Tropical Diseases: published May 8, 2017 | https://doi.org/10.1371/journal.pntd.0005594
Brugia malayi microfilariae adhere to human vascular endothelial cells in a C3-dependent manner
PLOS Neglected Tropical Diseases: published May 8, 2017 | https://doi.org/10.1371/journal.pntd.0005592
In a randomized trial, the live attenuated tetravalent dengue vaccine TV003 is well-tolerated and highly immunogenic in subjects with flavivirus exposure prior to vaccination
PLOS Neglected Tropical Diseases: published May 8, 2017 | https://doi.org/10.1371/journal.pntd.0005584
Associations between selective attention and soil-transmitted helminth infections, socioeconomic status, and physical fitness in disadvantaged children in Port Elizabeth, South Africa: An observational study
PLOS Neglected Tropical Diseases: published May 8, 2017 | https://doi.org/10.1371/journal.pntd.0005573
Yaws resurgence in Bankim, Cameroon: The relative effectiveness of different means of detection in rural communities
PLOS Neglected Tropical Diseases: published May 8, 2017 | https://doi.org/10.1371/journal.pntd.0005557
A nonsense mutation in TLR5 is associated with survival and reduced IL-10 and TNF-α levels in human melioidosis
PLOS Neglected Tropical Diseases: published May 5, 2017 | https://doi.org/10.1371/journal.pntd.0005587
The impact of migration and antimicrobial resistance on the transmission dynamics of typhoid fever in Kathmandu, Nepal: A mathematical modelling study
PLOS Neglected Tropical Diseases: published May 5, 2017 | https://doi.org/10.1371/journal.pntd.0005547
The effect of current Schistosoma mansoni infection on the immunogenicity of a candidate TB vaccine, MVA85A, in BCG-vaccinated adolescents: An open-label trial
PLOS Neglected Tropical Diseases: published May 4, 2017 | https://doi.org/10.1371/journal.pntd.0005440
A pilot study to delimit tsetse target populations in Zimbabwe
PLOS Neglected Tropical Diseases: published May 3, 2017 | https://doi.org/10.1371/journal.pntd.0005566
Interruption of persistent exposure to leprosy combined or not with recent BCG vaccination enhances the response to Mycobacterium leprae specific antigens
PLOS Neglected Tropical Diseases: published May 3, 2017 | https://doi.org/10.1371/journal.pntd.0005560
Safety and immunogenicity of the Na-GST-1 hookworm vaccine in Brazilian and American adults
PLOS Neglected Tropical Diseases: published May 2, 2017 | https://doi.org/10.1371/journal.pntd.0005574
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The clinical features of 590 patients with brucellosis in Xinjiang, China with the emphasis on the treatment of complications
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External quality assessment study for ebolavirus PCR-diagnostic promotes international preparedness during the 2014 – 2016 Ebola outbreak in West Africa
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Modulation of Mycobacterium tuberculosis-specific humoral immune responses is associated with Strongyloides stercoralis co-infection
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