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Table of Contents

January 2017

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Defining Abnormal Fetal Growth and Perinatal Risk: Population or Customized Standards?
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Appropriate fetal growth and development in utero is essential for newborn health and lifelong well-being. An aim of obstetric care is to detect fetuses at risk of complications from fetal growth disorders, and intervene to reduce the risk.

For this month's Editorial, Sarah Stock and Jenny Myers discuss different approaches to fetal and neonatal growth assessment in light of two new research articles published in this month's PLOS Medicine that contribute to the evidence base regarding the use of population charts for detection of fetal growth disorders and how best to determine risk of complications. They argue that the benefits of detecting fetal growth disorders can only be realized if we can effectively reduce risk of complications.

Image Credit: MedicalPrudens, Pixabay

Editorial

Defining Abnormal Fetal Growth and Perinatal Risk: Population or Customized Standards?

Sarah J. Stock, Jenny Myers

PLOS Medicine: published January 31, 2017 | https://doi.org/10.1371/journal.pmed.1002229

Perspectives

What Is the Purpose of the Orphan Drug Act?

Matthew Herder

PLOS Medicine: published January 3, 2017 | https://doi.org/10.1371/journal.pmed.1002191

Related Articles

  1. Biomarker-Defined Subsets of Common Diseases: Policy and Economic Implications of Orphan Drug Act Coverage

Sick Children Crying for Help: Fostering Adverse Event Reports

Gordon D. Schiff

PLOS Medicine: published January 17, 2017 | https://doi.org/10.1371/journal.pmed.1002216

Related Articles

  1. Patient Safety Incidents Involving Sick Children in Primary Care in England and Wales: A Mixed Methods Analysis

Novel Vector Control Approaches: The Future for Prevention of Zika Virus Transmission?

Lorenz von Seidlein, Alexander S. Kekulé, Daniel Strickman

PLOS Medicine: published January 17, 2017 | https://doi.org/10.1371/journal.pmed.1002219

Related Articles

  1. Mosquito-Disseminated Insecticide for Citywide Vector Control and Its Potential to Block Arbovirus Epidemics: Entomological Observations and Modeling Results from Amazonian Brazil

Health in Action

Bolstering Community Cooperation in Ebola Resurgence Protocols: Combining Field Blood Draw and Point-of-Care Diagnosis

Mosoka P. Fallah, Laura A. Skrip, Philomena Raftery, Miata Kullie, Watta Borbor, A. Scott Laney, David J. Blackley, Athalia Christie, Emily Kainne Dokubo, Terrence Q. Lo, Stewart Coulter, April Baller, Benjamin T. Vonhm, Philip Bemah, Sowillie Lomax, Adolphus Yeiah, Yatta Wapoe-Sackie, Jennifer Mann, Peter Clement, Gloria Davies-Wayne, Esther Hamblion, Caitlin Wolfe, Desmond Williams, Alex Gasasira, Francis Kateh, Tolbert G. Nyenswah, Alison P. Galvani

PLOS Medicine: published January 24, 2017 | https://doi.org/10.1371/journal.pmed.1002227

Policy Forums

Biomarker-Defined Subsets of Common Diseases: Policy and Economic Implications of Orphan Drug Act Coverage

Aaron S. Kesselheim, Carolyn L. Treasure, Steven Joffe

PLOS Medicine: published January 3, 2017 | https://doi.org/10.1371/journal.pmed.1002190

Related Articles

  1. What Is the Purpose of the Orphan Drug Act?

Artificially Sweetened Beverages and the Response to the Global Obesity Crisis

Maria Carolina Borges, Maria Laura Louzada, Thiago Hérick de Sá, Anthony A. Laverty, Diana C. Parra, Josefa Maria Fellegger Garzillo, Carlos Augusto Monteiro, Christopher Millett

PLOS Medicine: published January 3, 2017 | https://doi.org/10.1371/journal.pmed.1002195

Guidelines and Guidance

Reporting Items for Updated Clinical Guidelines: Checklist for the Reporting of Updated Guidelines (CheckUp)

Robin W. M. Vernooij, Pablo Alonso-Coello, Melissa Brouwers, Laura Martínez García, CheckUp Panel

PLOS Medicine: published January 10, 2017 | https://doi.org/10.1371/journal.pmed.1002207

Research Articles

Priority-Setting for Novel Drug Regimens to Treat Tuberculosis: An Epidemiologic Model

Emily A. Kendall, Sourya Shrestha, Ted Cohen, Eric Nuermberger, Kelly E. Dooley, Lice Gonzalez-Angulo, Gavin J. Churchyard, Payam Nahid, Michael L. Rich, Cathy Bansbach, Thomas Forissier, Christian Lienhardt, David W. Dowdy

PLOS Medicine: published January 3, 2017 | https://doi.org/10.1371/journal.pmed.1002202

Zika Virus Infection as a Cause of Congenital Brain Abnormalities and Guillain–Barré Syndrome: Systematic Review

Fabienne Krauer, Maurane Riesen, Ludovic Reveiz, Olufemi T. Oladapo, Ruth Martínez-Vega, Teegwendé V. Porgo, Anina Haefliger, Nathalie J. Broutet, Nicola Low, WHO Zika Causality Working Group

PLOS Medicine: published January 3, 2017 | https://doi.org/10.1371/journal.pmed.1002203

Effect of a Primary Care Walking Intervention with and without Nurse Support on Physical Activity Levels in 45- to 75-Year-Olds: The Pedometer And Consultation Evaluation (PACE-UP) Cluster Randomised Clinical Trial

Tess Harris, Sally M. Kerry, Elizabeth S. Limb, Christina R. Victor, Steve Iliffe, Michael Ussher, Peter H. Whincup, Ulf Ekelund, Julia Fox-Rushby, Cheryl Furness, Nana Anokye, Judith Ibison, Steve DeWilde, Lee David, Emma Howard, Rebecca Dale, Jaime Smith, Derek G. Cook

PLOS Medicine: published January 3, 2017 | https://doi.org/10.1371/journal.pmed.1002210

Population Pharmacokinetic Properties of Piperaquine in Falciparum Malaria: An Individual Participant Data Meta-Analysis

Richard M. Hoglund, Lesley Workman, Michael D. Edstein, Nguyen Xuan Thanh, Nguyen Ngoc Quang, Issaka Zongo, Jean Bosco Ouedraogo, Steffen Borrmann, Leah Mwai, Christian Nsanzabana, Ric N. Price, Prabin Dahal, Nancy C. Sambol, Sunil Parikh, Francois Nosten, Elizabeth A. Ashley, Aung Pyae Phyo, Khin Maung Lwin, Rose McGready, Nicholas P. J. Day, Philippe J. Guerin, Nicholas J. White, Karen I. Barnes, Joel Tarning

PLOS Medicine: published January 10, 2017 | https://doi.org/10.1371/journal.pmed.1002212

Socioeconomic Inequalities in Body Mass Index across Adulthood: Coordinated Analyses of Individual Participant Data from Three British Birth Cohort Studies Initiated in 1946, 1958 and 1970

David Bann, William Johnson, Leah Li, Diana Kuh, Rebecca Hardy

PLOS Medicine: published January 10, 2017 | https://doi.org/10.1371/journal.pmed.1002214

Mosquito-Disseminated Insecticide for Citywide Vector Control and Its Potential to Block Arbovirus Epidemics: Entomological Observations and Modeling Results from Amazonian Brazil

Fernando Abad-Franch, Elvira Zamora-Perea, Sérgio L. B. Luz

PLOS Medicine: published January 17, 2017 | https://doi.org/10.1371/journal.pmed.1002213

Related Articles

  1. Novel Vector Control Approaches: The Future for Prevention of Zika Virus Transmission?

Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach

Michael M. Mendelson, Riccardo E. Marioni, Roby Joehanes, Chunyu Liu, Åsa K. Hedman, Stella Aslibekyan, Ellen W. Demerath, Weihua Guan, Degui Zhi, Chen Yao, Tianxiao Huan, Christine Willinger, Brian Chen, Paul Courchesne, Michael Multhaup, Marguerite R. Irvin, Ariella Cohain, Eric E. Schadt, Megan L. Grove, Jan Bressler, Kari North, Johan Sundström, Stefan Gustafsson, Sonia Shah, Allan F. McRae, Sarah E. Harris, Jude Gibson, Paul Redmond, Janie Corley, Lee Murphy, John M. Starr, Erica Kleinbrink, Leonard Lipovich, Peter M. Visscher, Naomi R. Wray, Ronald M. Krauss, Daniele Fallin, Andrew Feinberg, Devin M. Absher, Myriam Fornage, James S. Pankow, Lars Lind, Caroline Fox, Erik Ingelsson, Donna K. Arnett, Eric Boerwinkle, Liming Liang, Daniel Levy, Ian J. Deary

PLOS Medicine: published January 17, 2017 | https://doi.org/10.1371/journal.pmed.1002215

Patient Safety Incidents Involving Sick Children in Primary Care in England and Wales: A Mixed Methods Analysis

Philippa Rees, Adrian Edwards, Colin Powell, Peter Hibbert, Huw Williams, Meredith Makeham, Ben Carter, Donna Luff, Gareth Parry, Anthony Avery, Aziz Sheikh, Liam Donaldson, Andrew Carson-Stevens

PLOS Medicine: published January 17, 2017 | https://doi.org/10.1371/journal.pmed.1002217

Related Articles

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Evaluating Hospital-Based Surveillance for Outbreak Detection in Bangladesh: Analysis of Healthcare Utilization Data

Birgit Nikolay, Henrik Salje, Katharine Sturm-Ramirez, Eduardo Azziz-Baumgartner, Nusrat Homaira, Makhdum Ahmed, A. Danielle Iuliano, Repon C. Paul, Mahmudur Rahman, M. Jahangir Hossain, Stephen P. Luby, Simon Cauchemez, Emily S. Gurley

PLOS Medicine: published January 17, 2017 | https://doi.org/10.1371/journal.pmed.1002218

The World Health Organization Fetal Growth Charts: A Multinational Longitudinal Study of Ultrasound Biometric Measurements and Estimated Fetal Weight

Torvid Kiserud, Gilda Piaggio, Guillermo Carroli, Mariana Widmer, José Carvalho, Lisa Neerup Jensen, Daniel Giordano, José Guilherme Cecatti, Hany Abdel Aleem, Sameera A. Talegawkar, Alexandra Benachi, Anke Diemert, Antoinette Tshefu Kitoto, Jadsada Thinkhamrop, Pisake Lumbiganon, Ann Tabor, Alka Kriplani, Rogelio Gonzalez Perez, Kurt Hecher, Mark A. Hanson, A. Metin Gülmezoglu, Lawrence D. Platt

PLOS Medicine: published January 24, 2017 | https://doi.org/10.1371/journal.pmed.1002220

Related Articles

  1. Correction: The World Health Organization Fetal Growth Charts: A Multinational Longitudinal Study of Ultrasound Biometric Measurements and Estimated Fetal Weight
  2. Correction: Correction: The World Health Organization Fetal Growth Charts: A Multinational Longitudinal Study of Ultrasound Biometric Measurements and Estimated Fetal Weight
  3. Correction: The World Health Organization Fetal Growth Charts: A Multinational Longitudinal Study of Ultrasound Biometric Measurements and Estimated Fetal Weight

Using Genetic Variation to Explore the Causal Effect of Maternal Pregnancy Adiposity on Future Offspring Adiposity: A Mendelian Randomisation Study

Rebecca C. Richmond, Nicholas J. Timpson, Janine F. Felix, Tom Palmer, Romy Gaillard, George McMahon, George Davey Smith, Vincent W. Jaddoe, Debbie A. Lawlor

PLOS Medicine: published January 24, 2017 | https://doi.org/10.1371/journal.pmed.1002221

Master Regulators of Oncogenic KRAS Response in Pancreatic Cancer: An Integrative Network Biology Analysis

Shivan Sivakumar, Ines de Santiago, Leon Chlon, Florian Markowetz

PLOS Medicine: published January 31, 2017 | https://doi.org/10.1371/journal.pmed.1002223

Customised and Noncustomised Birth Weight Centiles and Prediction of Stillbirth and Infant Mortality and Morbidity: A Cohort Study of 979,912 Term Singleton Pregnancies in Scotland

Stamatina Iliodromiti, Daniel F. Mackay, Gordon C. S. Smith, Jill P. Pell, Naveed Sattar, Debbie A. Lawlor, Scott M. Nelson

PLOS Medicine: published January 31, 2017 | https://doi.org/10.1371/journal.pmed.1002228