Trends in prescription opioid use and dose trajectories before opioid use disorder or overdose in US adults from 2006 to 2016: A cross-sectional study

• Yu-Jung Jenny Wei ,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Writing – original draft

  * E-mail: jenny.wei@cop.ufl.edu

  Affiliations Department of Pharmaceutical Outcomes and Policy, College of Pharmacy, University of Florida, Gainesville, Florida, United States of America, Center for Drug Evaluation and Safety, University of Florida, Gainesville, Florida, United States of America

  http://orcid.org/0000-0001-8861-6907

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• Cheng Chen,

  Roles Data curation, Investigation, Methodology

  Affiliation Department of Pharmaceutical Outcomes and Policy, College of Pharmacy, University of Florida, Gainesville, Florida, United States of America

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• Roger Fillingim,

  Roles Investigation, Writing – review & editing

  Affiliations College of Dentistry, University of Florida, Gainesville, Florida, United States of America, Pain Research and Intervention Center of Excellence, University of Florida, Gainesville, Florida, United States of America

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• Siegfried O. Schmidt,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Community Health and Family Medicine, College of Medicine, University of Florida, Gainesville, Florida, United States of America

  http://orcid.org/0000-0001-5941-6009

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• Almut G. Winterstein

  Roles Conceptualization, Investigation, Writing – review & editing

  Affiliations Department of Pharmaceutical Outcomes and Policy, College of Pharmacy, University of Florida, Gainesville, Florida, United States of America, Center for Drug Evaluation and Safety, University of Florida, Gainesville, Florida, United States of America, Department of Epidemiology, College of Medicine and College of Public Health & Health Professions, University of Florida, Gainesville, Florida, United States of America

  http://orcid.org/0000-0002-6518-5961

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