About the Authors
- Shama D. Ahuja
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Affiliation Bureau of Tuberculosis, New York, New York, United States of America
- David Ashkin
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Affiliation A.G. Holley Hospital, Lantana, Florida, United States of America
- Monika Avendano
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Affiliation University of Toronto, Toronto, Canada
- Rita Banerjee
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Affiliation Mayo Clinic, Rochester, Minnesota, United States of America
- Melissa Bauer
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Affiliation Montreal Chest Institute, McGill University, Montreal, Canada
- Jamie N. Bayona
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Affiliation The Dartmouth Center for Health Care Delivery Science, Hanover, New Hampshire, United States of America
- Mercedes C. Becerra
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Affiliations Harvard Medical School, Boston, Massachusetts, United States of America, Partners in Health, Boston, Massachusetts, United States of America
- Andrea Benedetti
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Affiliation Montreal Chest Institute, McGill University, Montreal, Canada
- Marcos Burgos
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Affiliation University of New Mexico School of Medicine, Albuquerque, New Mexico, United States of America
- Rosella Centis
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Affiliation WHO Collaborating Centre for TB and Lung Diseases, Care and Research Institute, Fondazione S. Maugeri, Tradate, Italy
- Eward D. Chan
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Affiliation Denver Veterans Affair Medical Center, Denver, Colorado, United States of America
- Chen-Yuan Chiang
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Affiliation Wan Fang Hospital, School of Medicine-Taipei Medical University, Taiwan
- Helen Cox
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Affiliation Médecins Sans Frontières, Capetown, South Africa
- Lia D'Ambrosio
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Affiliation WHO Collaborating Centre for TB and Lung Diseases, Care and Research Institute, Fondazione S. Maugeri, Tradate, Italy
- Kathy DeRiemer
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Affiliation UC Davis School of Medicine, Davis, California, United States of America
- Nguyen Huy Dung
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Affiliation National TB Control Program, Hanoi, Vietnam
- Donald Enarson
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Affiliation International Union against Tuberculosis and Lung Disease, Paris, France
- Dennis Falzon
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Affiliation World Health Organization, Geneva, Switzerland
- Katherine Flanagan
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Affiliation MRC Laboratories, Banjul, The Gambia
- Jennifer Flood
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Affiliation California Department of Public Health, Sacramento, California, United States of America
- Maria L. Garcia-Garcia
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Affiliation Instituto Nacional de Salud Pública, Mexico, Mexico
- Neel Gandhi
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Affiliation Albert Einstein College of Medicine, Bronx, New York, United States of America
- Reuben M. Granich
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Affiliation World Health Organization, Geneva, Switzerland
- Maria G. Hollm-Delgado
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Affiliation Montreal Chest Institute, McGill University, Montreal, Canada
- Timothy H. Holtz
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Affiliation Thailand MOPH & US CDC Collaboration, Bangkok, Thailand
- Michael D. Iseman
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Affiliation National Jewish Health, Denver, Colorado, United States of America
- Leah G. Jarlsberg
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Affiliation University of California, San Francisco, San Francisco, United States of America
- Salmaan Keshavjee
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Affiliation Harvard Medical School, Boston, Massachusetts, United States of America
- Hye-Ryoun Kim
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Affiliation Korea Cancer Center Hospital, Seoul, Korea
- Won-Jung Koh
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Affiliation Samsung Medical Center, Seoul, Korea
- Joey Lancaster
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Affiliation South African Medical Research Council, Pretoria, South Africa
- Christophe Lange
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Affiliation Medical Clinic, Tuberculosis Center Borstel, Borstel, Germany
- Wiel C. M. de Lange
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Affiliation University Medical Center Groningen, Groningen, The Netherlands
- Vaira Leimane
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Affiliation Clinic of Tuberculosis and Lung Diseases, Riga, Latvia
- Chi Chiu Leung
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Affiliation Tuberculosis and Chest Services, Hong Kong
- Jiehui Li
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Affiliation New York City Health and Mental Hygiene, New York, New York, United States of America
- Dick Menzies
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* E-mail: Dick.Menzies@McGill.ca
Affiliation Montreal Chest Institute, McGill University, Montreal, Canada
- Giovanni B. Migliori
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Affiliation WHO Collaborating Centre for TB and Lung Diseases, Care and Research Institute, Fondazione S. Maugeri, Tradate, Italy
- Sergey P. Mishustin
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Affiliation Tomsk Oblast Tuberculosis Dispensary, Tomsk, Russia
- Carole D. Mitnick
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Affiliation Harvard Medical School, Boston, Massachusetts, United States of America
- Masa Narita
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Affiliation University of Washington, Seattle, Washington, United States of America
- Philly O'Riordan
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Affiliation City Road Medical Centre, London, United Kingdom
- Madhukar Pai
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Affiliation Montreal Chest Institute, McGill University, Montreal, Canada
- Domingo Palmero
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Affiliation Hospital F.J. Muñiz, Buenos Aires, Argentina
- Seung-kyu Park
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Affiliation TB Center, Seoul, Korea
- Geoffrey Pasvol
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Affiliation Imperial College London, London, United Kingdom
- Jose Peña
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Affiliation Universidad Autonoma Madrid, Madrid, Spain
- Carlos Pérez-Guzmán
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Affiliation Instituto de Salud del Estado de Aguascalientes, Mexico, Mexico
- Maria I. D. Quelapio
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Affiliation Tropical Disease Foundation, Makati City, Philippines
- Alfredo Ponce-de-Leon
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Affiliation Instituto Nacional de Ciencias Médicas y de Nutrición “Salvador Zubirán”, Mexico, Mexico
- Vija Riekstina
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Affiliation Clinic of Tuberculosis and Lung Diseases, Riga, Latvia
- Jerome Robert
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Affiliation Bactériologie-Hygiène – UPMC, Paris, France
- Sarah Royce
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Affiliation University of California, San Francisco, San Francisco, United States of America
- H. Simon Schaaf
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Affiliation Stellenbosch University, Stellenbosch, South Africa
- Kwonjune J. Seung
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Affiliation Brigham and Women's Hospital, Boston, Massachusetts, United States of America
- Lena Shah
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Affiliation Montreal Chest Institute, McGill University, Montreal, Canada
- Tae Sun Shim
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Affiliation University of Ulsan College of Medicine, Seoul, Korea
- Sonya S. Shin
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Affiliation Brigham and Women's Hospital, Boston, Massachusetts, United States of America
- Yuji Shiraishi
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Affiliation Fukujuji Hospital, Tokyo, Japan
- José Sifuentes-Osornio
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Affiliation Instituto Nacional de Ciencias Médicas y de Nutrición “Salvador Zubirán”, Mexico, Mexico
- Giovanni Sotgiu
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Affiliation University of Sassari, Sassari, Italy
- Matthew J. Strand
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Affiliation National Jewish Health, Denver, Colorado, United States of America
- Payam Tabarsi
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Affiliation Shaheed Beheshti Medical University, Tehran, Iran
- Thelma E. Tupasi
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Affiliation Tropical Disease Foundation, Makati City, Philippines
- Robert van Altena
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Affiliation University Medical Center Groningen, Groningen, The Netherlands
- Martie Van der Walt
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Affiliation South African Medical Research Council, Pretoria, South Africa
- Tjip S. Van der Werf
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Affiliation University Medical Center Groningen, Groningen, The Netherlands
- Mario H. Vargas
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Affiliation Instituto Nacional de Enfermedades Respiratorias, Mexico, Mexico
- Pirett Viiklepp
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Affiliation National Institute for Health Development, Tallinn, Estonia
- Janice Westenhouse
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Affiliation Center for Infectious Diseases-California Department of Public Health, Sacramento, California, United States of America
- Wing Wai Yew
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Affiliation Grantham Hospital, Hong Kong
- Jae-Joon Yim
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All members of the Collaborative Group for Meta-Analysis of Individual Patient Data in MDR-TB are the authors and are listed in the manuscript byline.
Affiliation Seoul National University College of Medicine, Seoul, Korea
Competing Interests
JR is a Consultant for bioMérieux. WWY has been indirectly sponsored to participate in International Conferences by GlaxoSmithKline and Pfizer in the last 3 years. CDM is on the Scientific Advisory Board for Otsuka pharmaceuticals development of OPC67683 (Delaminid), a new anti-TB compound. SK received salary support from the Eli Lilly Foundation as part of funding for the activities of Partners In Health by the Foundation's MDR-TB Partnership. This funder was not involved in the study design; collection, analysis and interpretation of data; writing of the paper; and/or decision to submit for publication. The Partners In Health project in Tomsk received funding from Mr. Tom White, the Open Society Institute, the Bill and Melinda Gates Foundation, and the Global Fund to fight AIDS, Tuberculosis and Malaria. None of these funders were involved in the study design; collection, analysis and interpretation of data; writing of the paper; and/or decision to submit for publication. KD is an unpaid, volunteer member of the New Diagnostics Working Group (NDWG), formed of members of the Stop TB Partnership. The Secretariat of the NDWG is hosted by FIND (Foundation for New Innovative Diagnostics). JB was working as consultant for Otsuka Pharmaceutical for the implementation of clinical trial in Peru. JB was co PI of a NIH grant in Peru, Epidemiology of Tuberculosis. MP and GP are members of the Editorial Board of PLOS Medicine. All other authors have declared that no competing interests exist.
Author Contributions
Performed the experiments. Analyzed the data: SDA DA MA RB MBa JB MCB AB MBu RC EDC CYC HC LD KD NHD DE DF KF JF MLGG NRG RG MGHD THH MDI LGJ SK HRK WJK JLL CL WCMD VL CCL JL DM GBM SM CDM MN PO MP DP SKP GP JMP CPG MIDQ AP VR JR SR HSS KJS LS TSS SSS YS JSO GS MS PT TEP RVA MLV TSV MHV PV JW WWY JJY. Contributed reagents/materials/analysis tools: SDA DA MA RB MBa JB MCB AB MBu RC EDC CYC HC LD KD NHD DE DF KF JF MLGG NRG RG MGHD THH MDI LGJ SK HRK WJK JLL CL WCMD VL CCL JL DM GBM SM CDM MN PO MP DP SKP GP JMP CPG MIDQ AP VR JR SR HSS KJS LS TSS SSS YS JSO GS MS PT TEP RVA MLV TSV MHV PV JW WWY JJY. Wrote the first draft of the manuscript: DM. Contributed to the writing of the manuscript: SDA DA MA RB MBa JB MCB AB MBu RC EDC CYC HC LD KD NHD DE DF KF JF MLGG NRG RG MGHD THH MDI LGJ SK HRK WJK JLL CL WCMD VL CCL JL DM GBM SM CDM MN PO MP DP SKP GP JMP CPG MIDQ AP VR JR SR HSS KJS LS TSS SSS YS JSO GS MS PT TEP RVA MLV TSV MHV PV JW WWY JJY. ICMJE criteria for authorship read and met: SDA DA MA RB MBa JB MCB AB MBu RC EDC CYC HC LD KD NHD DE DF KF JF MLGG NRG RG MGHD THH MDI LGJ SK HRK WJK JLL CL WCMD VL CCL JL DM GBM SM CDM MN PO MP DP SKP GP JMP CPG MIDQ AP VR JR SR HSS KJS LS TSS SSS YS JSO GS MS PT TEP RVA MLV TSV MHV PV JW WWY JJY. Agree with manuscript results and conclusions: SDA DA MA RB MBa JB MCB AB MBu RC EDC CYC HC LD KD NHD DE DF KF JF MLGG NRG RG MGHD THH MDI LGJ SK HRK WJK JLL CL WCMD VL CCL JL DM GBM SM CDM MN PO MP DP SKP GP JMP CPG MIDQ AP VR JR SR HSS KJS LS TSS SSS YS JSO GS MS PT TEP RVA MLV TSV MHV PV JW WWY JJY.