Scientists use mathematical modeling to simulate human mesenchymal stem cell delivery to the heart and found that using one subtype of these stem cells minimises the risks associated with this therapy. Mayourian et al.
Image Credit: Joshua Mayourian
Editorials
Ten Simple Rules for Curating and Facilitating Small Workshops
PLOS Computational Biology: published July 21, 2016 | https://doi.org/10.1371/journal.pcbi.1004745
Ten Simple Rules for Writing a Postdoctoral Fellowship
PLOS Computational Biology: published July 14, 2016 | https://doi.org/10.1371/journal.pcbi.1004934
Ten Simple Rules for Taking Advantage of Git and GitHub
PLOS Computational Biology: published July 14, 2016 | https://doi.org/10.1371/journal.pcbi.1004947
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Computing Biology
PLOS Computational Biology: published July 12, 2016 | https://doi.org/10.1371/journal.pcbi.1005050
Message from ISCB
2016 ISCB Innovator Award: Serafim Batzoglou
PLOS Computational Biology: published July 7, 2016 | https://doi.org/10.1371/journal.pcbi.1004973
Topic Page
Ancestral Reconstruction
PLOS Computational Biology: published July 12, 2016 | https://doi.org/10.1371/journal.pcbi.1004763
Research Articles
PhyloBot: A Web Portal for Automated Phylogenetics, Ancestral Sequence Reconstruction, and Exploration of Mutational Trajectories
PLOS Computational Biology: published July 29, 2016 | https://doi.org/10.1371/journal.pcbi.1004976
Improvement in Protein Domain Identification Is Reached by Breaking Consensus, with the Agreement of Many Profiles and Domain Co-occurrence
PLOS Computational Biology: published July 29, 2016 | https://doi.org/10.1371/journal.pcbi.1005038
The Differential Response of Proteins to Macromolecular Crowding
PLOS Computational Biology: published July 29, 2016 | https://doi.org/10.1371/journal.pcbi.1005040
Context Specific and Differential Gene Co-expression Networks via Bayesian Biclustering
PLOS Computational Biology: published July 28, 2016 | https://doi.org/10.1371/journal.pcbi.1004791
A Multi-scale Computational Platform to Mechanistically Assess the Effect of Genetic Variation on Drug Responses in Human Erythrocyte Metabolism
PLOS Computational Biology: published July 28, 2016 | https://doi.org/10.1371/journal.pcbi.1005039
Model-Based Characterization of Inflammatory Gene Expression Patterns of Activated Macrophages
PLOS Computational Biology: published July 27, 2016 | https://doi.org/10.1371/journal.pcbi.1005018
Multiscale Simulations Suggest a Mechanism for the Association of the Dok7 PH Domain with PIP-Containing Membranes
PLOS Computational Biology: published July 26, 2016 | https://doi.org/10.1371/journal.pcbi.1005028
Modeling Electrophysiological Coupling and Fusion between Human Mesenchymal Stem Cells and Cardiomyocytes
PLOS Computational Biology: published July 25, 2016 | https://doi.org/10.1371/journal.pcbi.1005014
Modeling of Kidney Hemodynamics: Probability-Based Topology of an Arterial Network
PLOS Computational Biology: published July 22, 2016 | https://doi.org/10.1371/journal.pcbi.1004922
How People Use Social Information to Find out What to Want in the Paradigmatic Case of Inter-temporal Preferences
PLOS Computational Biology: published July 22, 2016 | https://doi.org/10.1371/journal.pcbi.1004965
Inference for Stochastic Chemical Kinetics Using Moment Equations and System Size Expansion
PLOS Computational Biology: published July 22, 2016 | https://doi.org/10.1371/journal.pcbi.1005030
Robust Inference of Cell-to-Cell Expression Variations from Single- and K-Cell Profiling
PLOS Computational Biology: published July 20, 2016 | https://doi.org/10.1371/journal.pcbi.1005016
Learning to Predict miRNA-mRNA Interactions from AGO CLIP Sequencing and CLASH Data
PLOS Computational Biology: published July 20, 2016 | https://doi.org/10.1371/journal.pcbi.1005026
Reinforcement Learning Explains Conditional Cooperation and Its Moody Cousin
PLOS Computational Biology: published July 20, 2016 | https://doi.org/10.1371/journal.pcbi.1005034
Near Equilibrium Calculus of Stem Cells in Application to the Airway Epithelium Lineage
PLOS Computational Biology: published July 18, 2016 | https://doi.org/10.1371/journal.pcbi.1004990
The Integrated Role of Wnt/β-Catenin, N-Glycosylation, and E-Cadherin-Mediated Adhesion in Network Dynamics
PLOS Computational Biology: published July 18, 2016 | https://doi.org/10.1371/journal.pcbi.1005007
ASSET: Analysis of Sequences of Synchronous Events in Massively Parallel Spike Trains
PLOS Computational Biology: published July 15, 2016 | https://doi.org/10.1371/journal.pcbi.1004939
Disease Surveillance on Complex Social Networks
PLOS Computational Biology: published July 14, 2016 | https://doi.org/10.1371/journal.pcbi.1004928
NLLSS: Predicting Synergistic Drug Combinations Based on Semi-supervised Learning
PLOS Computational Biology: published July 14, 2016 | https://doi.org/10.1371/journal.pcbi.1004975
Phasic Burst Stimulation: A Closed-Loop Approach to Tuning Deep Brain Stimulation Parameters for Parkinson’s Disease
PLOS Computational Biology: published July 14, 2016 | https://doi.org/10.1371/journal.pcbi.1005011
Intrinsic Valuation of Information in Decision Making under Uncertainty
PLOS Computational Biology: published July 14, 2016 | https://doi.org/10.1371/journal.pcbi.1005020
A Computational Modeling and Simulation Approach to Investigate Mechanisms of Subcellular cAMP Compartmentation
PLOS Computational Biology: published July 13, 2016 | https://doi.org/10.1371/journal.pcbi.1005005
Modelling of Yeast Mating Reveals Robustness Strategies for Cell-Cell Interactions
PLOS Computational Biology: published July 12, 2016 | https://doi.org/10.1371/journal.pcbi.1004988
Integrating Transcriptomic and Proteomic Data Using Predictive Regulatory Network Models of Host Response to Pathogens
PLOS Computational Biology: published July 12, 2016 | https://doi.org/10.1371/journal.pcbi.1005013
Machine Learning Meta-analysis of Large Metagenomic Datasets: Tools and Biological Insights
PLOS Computational Biology: published July 11, 2016 | https://doi.org/10.1371/journal.pcbi.1004977
Metagenome and Metatranscriptome Analyses Using Protein Family Profiles
PLOS Computational Biology: published July 11, 2016 | https://doi.org/10.1371/journal.pcbi.1004991
Dynamic Reweighting of Auditory Modulation Filters
PLOS Computational Biology: published July 11, 2016 | https://doi.org/10.1371/journal.pcbi.1005019
The Emergence of Synaesthesia in a Neuronal Network Model via Changes in Perceptual Sensitivity and Plasticity
PLOS Computational Biology: published July 8, 2016 | https://doi.org/10.1371/journal.pcbi.1004959
Properties of Neurons in External Globus Pallidus Can Support Optimal Action Selection
PLOS Computational Biology: published July 7, 2016 | https://doi.org/10.1371/journal.pcbi.1005004
Using Combined Diagnostic Test Results to Hindcast Trends of Infection from Cross-Sectional Data
PLOS Computational Biology: published July 6, 2016 | https://doi.org/10.1371/journal.pcbi.1004901
The More the Tubular: Dynamic Bundling of Actin Filaments for Membrane Tube Formation
PLOS Computational Biology: published July 6, 2016 | https://doi.org/10.1371/journal.pcbi.1004982
The Coda of the Transient Response in a Sensitive Cochlea: A Computational Modeling Study
PLOS Computational Biology: published July 5, 2016 | https://doi.org/10.1371/journal.pcbi.1005015
Cellular Interrogation: Exploiting Cell-to-Cell Variability to Discriminate Regulatory Mechanisms in Oscillatory Signalling
PLOS Computational Biology: published July 1, 2016 | https://doi.org/10.1371/journal.pcbi.1004995
Collective Signal Processing in Cluster Chemotaxis: Roles of Adaptation, Amplification, and Co-attraction in Collective Guidance
PLOS Computational Biology: published July 1, 2016 | https://doi.org/10.1371/journal.pcbi.1005008