Figures
Mapping of soft disorder residues and interface regions in alternative crystals of p53
The DNA binding domain of protein p53 is found complexed with many other proteins and DNA in the Protein Data Bank (PDB). The outer wheel shows soft disordered (in orange) and interface (in blue) regions observed in alternative crystals of these complexes. In the center, we show that once mapped on the structure, the union of all soft disordered regions and the union of all the interface regions tend to involve the same amino acids in the protein.
Image Credit: Beatriz Seoane
Citation: (2021) PLoS Computational Biology Issue Image | Vol. 17(1) February 2021. PLoS Comput Biol 17(1): ev17.i01. https://doi.org/10.1371/image.pcbi.v17.i01
Published: February 2, 2021
Copyright: © 2021 . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The DNA binding domain of protein p53 is found complexed with many other proteins and DNA in the Protein Data Bank (PDB). The outer wheel shows soft disordered (in orange) and interface (in blue) regions observed in alternative crystals of these complexes. In the center, we show that once mapped on the structure, the union of all soft disordered regions and the union of all the interface regions tend to involve the same amino acids in the protein.
Image Credit: Beatriz Seoane