Brain Modeling ToolKit: An open source software suite for multiscale modeling of brain circuits
Fig 4
Biophysically detailed, point-neuron, and population simulations with BioNet, PointNet, and PopNet.
In all three cases, the interconnected populations of excitatory and inhibitory neurons receive excitatory input from an external population (1,000 Poisson sources firing at the frequency of 150 Hz, replaced by a uniform population in the PopNet case). (A) Biophysically detailed network of randomly connected excitatory and inhibitory neurons, 12,500 total. An RTNeuron visualization of the network is shown alongside its spiking output (spikes from a small portion of the network are shown, for clarity) and the firing rate (for the whole excitatory population) produced by the BMTK’s BioNet module. (B) The same network using the point-neuron approximation. An RTNeuron visualization and simulation output from the BMTK’s PointNet module simulation are shown. (C) Population-based representation of the same network. A schematic of the model and the output of population-density simulation (firing rate for the excitatory population is shown) from BMTK’s PopNet module are illustrated.