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Efficiency and Power as a Function of Sequence Coverage, SNP Array Density, and Imputation

Figure 3

Data collection strategies for studies with prior array data.

For the (a) Affy 6 and (b) Ilmn 1 M arrays, we produced joint calls after addition of each sequence coverage or array; joint calls with multiple arrays include combined data from both arrays. The y-axis shows , while the x-axis shows of the additional data collected. is a measure of the genotyping investment intrinsic to a technology that serves as a proxy for cost. The blue point (None) shows if no additional data is collected; the other points are labeled with the additional data collected. Labels are defined in 2.

doi: https://doi.org/10.1371/journal.pcbi.1002604.g003