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Open Access
Peer-reviewed
Research Article
Optimal tuning of weighted kNN- and diffusion-based methods for denoising single cell genomics data
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Andreas Tjärnberg ,
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing
* E-mail: andreas.tjarnberg@nyu.edu (AT); rb133@nyu.edu (RAB)
Affiliations Center for Developmental Genetics, New York University, New York, New York, USA, Center For Genomics and Systems Biology, NYU, New York, New York, USA, Department of Biology, NYU, New York, New York, USA
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Omar Mahmood ,
Contributed equally to this work with: Omar Mahmood, Christopher A. Jackson
Roles Formal analysis, Software, Visualization, Writing – original draft, Writing – review & editing
Affiliation Center For Data Science, NYU, New York, New York, USA
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Christopher A. Jackson ,
Contributed equally to this work with: Omar Mahmood, Christopher A. Jackson
Roles Data curation, Formal analysis, Software, Visualization, Writing – original draft, Writing – review & editing
Affiliations Center For Genomics and Systems Biology, NYU, New York, New York, USA, Department of Biology, NYU, New York, New York, USA
⨯ - Giuseppe-Antonio Saldi,
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Kyunghyun Cho,
Roles Supervision, Writing – original draft, Writing – review & editing
Affiliations Flatiron Institute, Center for Computational Biology, Simons Foundation, New York, New York, USA, Courant Institute of Mathematical Sciences, Computer Science Department, New York University, New York, New York, USA
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Lionel A. Christiaen,
Roles Resources, Supervision, Writing – original draft, Writing – review & editing
Affiliations Center for Developmental Genetics, New York University, New York, New York, USA, Department of Biology, NYU, New York, New York, USA
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Richard A. Bonneau
Roles Conceptualization, Investigation, Resources, Supervision, Writing – original draft, Writing – review & editing
* E-mail: andreas.tjarnberg@nyu.edu (AT); rb133@nyu.edu (RAB)
Affiliations Center For Genomics and Systems Biology, NYU, New York, New York, USA, Department of Biology, NYU, New York, New York, USA, Center For Data Science, NYU, New York, New York, USA, Flatiron Institute, Center for Computational Biology, Simons Foundation, New York, New York, USA, Courant Institute of Mathematical Sciences, Computer Science Department, New York University, New York, New York, USA
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Optimal tuning of weighted kNN- and diffusion-based methods for denoising single cell genomics data
- Andreas Tjärnberg,
- Omar Mahmood,
- Christopher A. Jackson,
- Giuseppe-Antonio Saldi,
- Kyunghyun Cho,
- Lionel A. Christiaen,
- Richard A. Bonneau
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- Published: January 7, 2021
- https://doi.org/10.1371/journal.pcbi.1008569