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Open Access
Peer-reviewed
Research Article
Deconvolving multiplexed protease signatures with substrate reduction and activity clustering
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Qinwei Zhuang ,
Contributed equally to this work with: Qinwei Zhuang, Brandon Alexander Holt
Roles Data curation, Formal analysis, Software, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliation School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, United States of America
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Brandon Alexander Holt ,
Contributed equally to this work with: Qinwei Zhuang, Brandon Alexander Holt
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliation Wallace H. Coulter Department of Biomedical Engineering, Georgia Tech College of Engineering and Emory School of Medicine, Atlanta, Georgia, United States of America
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Gabriel A. Kwong ,
Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing
* E-mail: gkwong@gatech.edu (GAK); peng.qiu@bme.gatech.edu (PQ)
Affiliations Wallace H. Coulter Department of Biomedical Engineering, Georgia Tech College of Engineering and Emory School of Medicine, Atlanta, Georgia, United States of America, Parker H. Petit Institute of Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia, United States of America, Institute for Electronics and Nanotechnology, Georgia Institute of Technology, Atlanta, Georgia, United States of America, Integrated Cancer Research Center, Georgia Institute of Technology, Atlanta, Georgia, United States of America, Georgia ImmunoEngineering Consortium, Georgia Tech and Emory University, Atlanta, Georgia, United States of America
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Peng Qiu
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing
* E-mail: gkwong@gatech.edu (GAK); peng.qiu@bme.gatech.edu (PQ)
Affiliations Wallace H. Coulter Department of Biomedical Engineering, Georgia Tech College of Engineering and Emory School of Medicine, Atlanta, Georgia, United States of America, Parker H. Petit Institute of Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia, United States of America
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Deconvolving multiplexed protease signatures with substrate reduction and activity clustering
- Qinwei Zhuang,
- Brandon Alexander Holt,
- Gabriel A. Kwong,
- Peng Qiu
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- Published: September 3, 2019
- https://doi.org/10.1371/journal.pcbi.1006909