Thermodynamics-Based Models of Transcriptional Regulation by Enhancers: The Roles of Synergistic Activation, Cooperative Binding and Short-Range Repression

Open Access

Peer-reviewed

Research Article

Xin He,

Affiliation Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, California, United States of America
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Md. Abul Hassan Samee,

Affiliation Department of Computer Science, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America
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Charles Blatti,

Affiliation Department of Computer Science, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America
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Saurabh Sinha

* E-mail: sinhas@illinois.edu

Affiliation Department of Computer Science, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America
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Gene expression
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Transcription factors
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DNA transcription
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Transcriptional control
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Gene regulation
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Chromatin
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Drosophila melanogaster
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Statistical mechanics
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