Hybridization in Parasites: Consequences for Adaptive Evolution, Pathogenesis, and Public Health in a Changing World

Kayla C. King, Rike B. Stelkens, Joanne P. Webster, Deborah F. Smith, Michael A. Brockhurst

PLOS Pathogens: published September 3, 2015 | https://doi.org/10.1371/journal.ppat.1005098

Epicellular Apicomplexans: Parasites “On the Way In”

Pavla Bartošová-Sojková, Rebecca D. Oppenheim, Dominique Soldati-Favre, Julius Lukeš

PLOS Pathogens: published September 24, 2015 | https://doi.org/10.1371/journal.ppat.1005080

Knocking on Closed Doors: Host Interferons Dynamically Regulate Blood-Brain Barrier Function during Viral Infections of the Central Nervous System

Brian P. Daniels, Robyn S. Klein

PLOS Pathogens: published September 17, 2015 | https://doi.org/10.1371/journal.ppat.1005096

Fiat Luc: Bioluminescence Imaging Reveals In Vivo Viral Replication Dynamics

Andrew Mehle

PLOS Pathogens: published September 10, 2015 | https://doi.org/10.1371/journal.ppat.1005081

Ross River Virus: Many Vectors and Unusual Hosts Make for an Unpredictable Pathogen

Suzi B. Claflin, Cameron E. Webb

PLOS Pathogens: published September 3, 2015 | https://doi.org/10.1371/journal.ppat.1005070

Microbial Regulation of p53 Tumor Suppressor

Alexander I. Zaika, Jinxiong Wei, Jennifer M. Noto, Richard M. Peek

PLOS Pathogens: published September 17, 2015 | https://doi.org/10.1371/journal.ppat.1005099

Appetite for a Foodborne Infection

Vern B. Carruthers

PLOS Pathogens: published September 24, 2015 | https://doi.org/10.1371/journal.ppat.1005124

Here I Am, Despite Myself

Glenn Rall

PLOS Pathogens: published September 10, 2015 | https://doi.org/10.1371/journal.ppat.1005106

Conserved Motifs within Hepatitis C Virus Envelope (E2) RNA and Protein Independently Inhibit T Cell Activation

Nirjal Bhattarai, James H. McLinden, Jinhua Xiang, Thomas M. Kaufman, Jack T. Stapleton

PLOS Pathogens: published September 30, 2015 | https://doi.org/10.1371/journal.ppat.1005183

Plasmodium Infection Is Associated with Impaired Hepatic Dimethylarginine Dimethylaminohydrolase Activity and Disruption of Nitric Oxide Synthase Inhibitor/Substrate Homeostasis

Jessica H. Chertow, Matthew S. Alkaitis, Glenn Nardone, Allison K. Ikeda, Aubrey J. Cunnington, Joseph Okebe, Augustine O. Ebonyi, Madi Njie, Simon Correa, Shamanthi Jayasooriya, Climent Casals-Pascual, Oliver Billker, David J. Conway, Michael Walther, Hans Ackerman

PLOS Pathogens: published September 25, 2015 | https://doi.org/10.1371/journal.ppat.1005119

Global Analysis of Mouse Polyomavirus Infection Reveals Dynamic Regulation of Viral and Host Gene Expression and Promiscuous Viral RNA Editing

Seth B. Garren, Yuvabharath Kondaveeti, Michael O. Duff, Gordon G. Carmichael

PLOS Pathogens: published September 25, 2015 | https://doi.org/10.1371/journal.ppat.1005166

DYRK2 Negatively Regulates Type I Interferon Induction by Promoting TBK1 Degradation via Ser527 Phosphorylation

Tai An, Shu Li, Wei Pan, Po Tien, Bo Zhong, Hong-Bing Shu, Shuwen Wu

PLOS Pathogens: published September 25, 2015 | https://doi.org/10.1371/journal.ppat.1005179

Prevention of Influenza Virus-Induced Immunopathology by TGF-β Produced during Allergic Asthma

Yoichi Furuya, Andrea K. M. Furuya, Sean Roberts, Alan M. Sanfilippo, Sharon L. Salmon, Dennis W. Metzger

PLOS Pathogens: published September 25, 2015 | https://doi.org/10.1371/journal.ppat.1005180

The Deacetylase Sirtuin 1 Regulates Human Papillomavirus Replication by Modulating Histone Acetylation and Recruitment of DNA Damage Factors NBS1 and Rad51 to Viral Genomes

Erika S. Langsfeld, Jason M. Bodily, Laimonis A. Laimins

PLOS Pathogens: published September 25, 2015 | https://doi.org/10.1371/journal.ppat.1005181

Modulation of the Host Lipid Landscape to Promote RNA Virus Replication: The Picornavirus Encephalomyocarditis Virus Converges on the Pathway Used by Hepatitis C Virus

Cristina M. Dorobantu, Lucian Albulescu, Christian Harak, Qian Feng, Mirjam van Kampen, Jeroen R. P. M. Strating, Alexander E. Gorbalenya, Volker Lohmann, Hilde M. van der Schaar, Frank J. M. van Kuppeveld

PLOS Pathogens: published September 25, 2015 | https://doi.org/10.1371/journal.ppat.1005185

Experimental Malaria in Pregnancy Induces Neurocognitive Injury in Uninfected Offspring via a C5a-C5a Receptor Dependent Pathway

Chloë R. McDonald, Lindsay S. Cahill, Keith T. Ho, Jimmy Yang, Hani Kim, Karlee L. Silver, Peter A. Ward, Howard T. Mount, W. Conrad Liles, John G. Sled, Kevin C. Kain

PLOS Pathogens: published September 24, 2015 | https://doi.org/10.1371/journal.ppat.1005140

Adipose Tissue Is a Neglected Viral Reservoir and an Inflammatory Site during Chronic HIV and SIV Infection

Abderaouf Damouche, Thierry Lazure, Véronique Avettand-Fènoël, Nicolas Huot, Nathalie Dejucq-Rainsford, Anne-Pascale Satie, Adeline Mélard, Ludivine David, Céline Gommet, Jade Ghosn, Nicolas Noel, Guillaume Pourcher, Valérie Martinez, Stéphane Benoist, Véronique Béréziat, Antonio Cosma, Benoit Favier, Bruno Vaslin, Christine Rouzioux, Jacqueline Capeau, Michaela Müller-Trutwin, Nathalie Dereuddre-Bosquet, Roger Le Grand, Olivier Lambotte, Christine Bourgeois

PLOS Pathogens: published September 24, 2015 | https://doi.org/10.1371/journal.ppat.1005153

A KSHV microRNA Directly Targets G Protein-Coupled Receptor Kinase 2 to Promote the Migration and Invasion of Endothelial Cells by Inducing CXCR2 and Activating AKT Signaling

Minmin Hu, Cong Wang, Wan Li, Weiping Lu, Zhiqiang Bai, Di Qin, Qin Yan, Jianzhong Zhu, Brian J. Krueger, Rolf Renne, Shou-Jiang Gao, Chun Lu

PLOS Pathogens: published September 24, 2015 | https://doi.org/10.1371/journal.ppat.1005171

The Role of the Antiviral APOBEC3 Gene Family in Protecting Chimpanzees against Lentiviruses from Monkeys

Lucie Etienne, Frederic Bibollet-Ruche, Peter H. Sudmant, Lily I. Wu, Beatrice H. Hahn, Michael Emerman

PLOS Pathogens: published September 22, 2015 | https://doi.org/10.1371/journal.ppat.1005149

The Depsipeptide Romidepsin Reverses HIV-1 Latency In Vivo

Ole S. Søgaard, Mette E. Graversen, Steffen Leth, Rikke Olesen, Christel R. Brinkmann, Sara K. Nissen, Anne Sofie Kjaer, Mariane H. Schleimann, Paul W. Denton, William J. Hey-Cunningham, Kersten K. Koelsch, Giuseppe Pantaleo, Kim Krogsgaard, Maja Sommerfelt, Remi Fromentin, Nicolas Chomont, Thomas A. Rasmussen, Lars Østergaard, Martin Tolstrup

PLOS Pathogens: published September 17, 2015 | https://doi.org/10.1371/journal.ppat.1005142

Heterosexual Transmission of Subtype C HIV-1 Selects Consensus-Like Variants without Increased Replicative Capacity or Interferon-α Resistance

Martin J. Deymier, Zachary Ende, Angharad E. Fenton-May, Dario A. Dilernia, William Kilembe, Susan A. Allen, Persephone Borrow, Eric Hunter

PLOS Pathogens: published September 17, 2015 | https://doi.org/10.1371/journal.ppat.1005154

ADAP2 Is an Interferon Stimulated Gene That Restricts RNA Virus Entry

Qian Shu, Nicholas J. Lennemann, Saumendra N. Sarkar, Yoel Sadovsky, Carolyn B. Coyne

PLOS Pathogens: published September 15, 2015 | https://doi.org/10.1371/journal.ppat.1005150

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Skin-Derived C-Terminal Filaggrin-2 Fragments Are Pseudomonas aeruginosa-Directed Antimicrobials Targeting Bacterial Replication

Britta Hansmann, Jens-Michael Schröder, Ulrich Gerstel

PLOS Pathogens: published September 15, 2015 | https://doi.org/10.1371/journal.ppat.1005159

The Borrelia burgdorferi RelA/SpoT Homolog and Stringent Response Regulate Survival in the Tick Vector and Global Gene Expression during Starvation

Dan Drecktrah, Meghan Lybecker, Niko Popitsch, Philipp Rescheneder, Laura S. Hall, D. Scott Samuels

PLOS Pathogens: published September 15, 2015 | https://doi.org/10.1371/journal.ppat.1005160

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The NLRP3 Inflammasome and IL-1β Accelerate Immunologically Mediated Pathology in Experimental Viral Fulminant Hepatitis

Sheng Guo, Chengying Yang, Bo Diao, Xiaoyong Huang, Meihua Jin, Lili Chen, Weiming Yan, Qin Ning, Lixin Zheng, Yuzhang Wu, Yongwen Chen

PLOS Pathogens: published September 14, 2015 | https://doi.org/10.1371/journal.ppat.1005155

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Intrinsic MyD88-Akt1-mTOR Signaling Coordinates Disparate Tc17 and Tc1 Responses during Vaccine Immunity against Fungal Pneumonia

Som Gowda Nanjappa, Nydiaris Hernández-Santos, Kevin Galles, Marcel Wüthrich, M. Suresh, Bruce S. Klein

PLOS Pathogens: published September 14, 2015 | https://doi.org/10.1371/journal.ppat.1005161

Neisseria meningitidis Type IV Pili Composed of Sequence Invariable Pilins Are Masked by Multisite Glycosylation

Joseph Gault, Mathias Ferber, Silke Machata, Anne-Flore Imhaus, Christian Malosse, Arthur Charles-Orszag, Corinne Millien, Guillaume Bouvier, Benjamin Bardiaux, Gérard Péhau-Arnaudet, Kelly Klinge, Isabelle Podglajen, Marie Cécile Ploy, H. Steven Seifert, Michael Nilges, Julia Chamot-Rooke, Guillaume Duménil

PLOS Pathogens: published September 14, 2015 | https://doi.org/10.1371/journal.ppat.1005162

Simian Immunodeficiency Virus Infection of Chimpanzees (Pan troglodytes) Shares Features of Both Pathogenic and Non-pathogenic Lentiviral Infections

Edward J. D. Greenwood, Fabian Schmidt, Ivanela Kondova, Henk Niphuis, Vida L. Hodara, Leah Clissold, Kirsten McLay, Bernadette Guerra, Sharon Redrobe, Luis D. Giavedoni, Robert E. Lanford, Krishna K. Murthy, François Rouet, Jonathan L. Heeney

PLOS Pathogens: published September 11, 2015 | https://doi.org/10.1371/journal.ppat.1005146

Intrahepatic Transcriptional Signature Associated with Response to Interferon-α Treatment in the Woodchuck Model of Chronic Hepatitis B

Simon P. Fletcher, Daniel J. Chin, Lore Gruenbaum, Hans Bitter, Erik Rasmussen, Palanikumar Ravindran, David C. Swinney, Fabian Birzele, Roland Schmucki, Stefan H. Lorenz, Erhard Kopetzki, Jade Carter, Miriam Triyatni, Linta M. Thampi, Junming Yang, Dalal AlDeghaither, Marta G. Murredu, Paul Cote, Stephan Menne

PLOS Pathogens: published September 9, 2015 | https://doi.org/10.1371/journal.ppat.1005103

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Rapid Lymphatic Dissemination of Encapsulated Group A Streptococci via Lymphatic Vessel Endothelial Receptor-1 Interaction

Nicola N. Lynskey, Suneale Banerji, Louise A. Johnson, Kayla A. Holder, Mark Reglinski, Peter A. C. Wing, David Rigby, David G. Jackson, Shiranee Sriskandan

PLOS Pathogens: published September 9, 2015 | https://doi.org/10.1371/journal.ppat.1005137

Porphyromonas gingivalis Type IX Secretion Substrates Are Cleaved and Modified by a Sortase-Like Mechanism

Dhana G. Gorasia, Paul D. Veith, Dina Chen, Christine A. Seers, Helen A. Mitchell, Yu-Yen Chen, Michelle D. Glew, Stuart G. Dashper, Eric C. Reynolds

PLOS Pathogens: published September 4, 2015 | https://doi.org/10.1371/journal.ppat.1005152

Immunostimulatory Defective Viral Genomes from Respiratory Syncytial Virus Promote a Strong Innate Antiviral Response during Infection in Mice and Humans

Yan Sun, Deepika Jain, Cynthia J. Koziol-White, Emmanuelle Genoyer, Micah Gilbert, Karla Tapia, Reynold A. Panettieri Jr., Richard L. Hodinka, Carolina B. López

PLOS Pathogens: published September 3, 2015 | https://doi.org/10.1371/journal.ppat.1005122

Distinct but Spatially Overlapping Intestinal Niches for Vancomycin-Resistant Enterococcus faecium and Carbapenem-Resistant Klebsiella pneumoniae

Silvia Caballero, Rebecca Carter, Xu Ke, Bože Sušac, Ingrid M. Leiner, Grace J. Kim, Liza Miller, Lilan Ling, Katia Manova, Eric G. Pamer

PLOS Pathogens: published September 3, 2015 | https://doi.org/10.1371/journal.ppat.1005132

Intracellular Survival of Leishmania major Depends on Uptake and Degradation of Extracellular Matrix Glycosaminoglycans by Macrophages

Thomas Naderer, Joanne Heng, Eleanor C. Saunders, Joachim Kloehn, Thusitha W. Rupasinghe, Tracey J. Brown, Malcolm J. McConville

PLOS Pathogens: published September 3, 2015 | https://doi.org/10.1371/journal.ppat.1005136

Inhibition of Translation Initiation by Protein 169: A Vaccinia Virus Strategy to Suppress Innate and Adaptive Immunity and Alter Virus Virulence

Pavla Strnadova, Hongwei Ren, Robert Valentine, Michela Mazzon, Trevor R. Sweeney, Ian Brierley, Geoffrey L. Smith

PLOS Pathogens: published September 3, 2015 | https://doi.org/10.1371/journal.ppat.1005151

Enteropathogenic Escherichia coli Uses NleA to Inhibit NLRP3 Inflammasome Activation

Hilo Yen, Nakaba Sugimoto, Toru Tobe

PLOS Pathogens: published September 2, 2015 | https://doi.org/10.1371/journal.ppat.1005121

Suppression of a Natural Killer Cell Response by Simian Immunodeficiency Virus Peptides

Jamie L. Schafer, Moritz Ries, Natasha Guha, Michelle Connole, Arnaud D. Colantonio, Emmanuel J. Wiertz, Nancy A. Wilson, Amitinder Kaur, David T. Evans

PLOS Pathogens: published September 2, 2015 | https://doi.org/10.1371/journal.ppat.1005145

KSHV Latency Locus Cooperates with Myc to Drive Lymphoma in Mice

Sang-Hoon Sin, Yongbaek Kim, Anthony Eason, Dirk P. Dittmer

PLOS Pathogens: published September 1, 2015 | https://doi.org/10.1371/journal.ppat.1005135

Cullin4 Is Pro-Viral during West Nile Virus Infection of Culex Mosquitoes

Prasad N. Paradkar, Jean-Bernard Duchemin, Julio Rodriguez-Andres, Lee Trinidad, Peter J. Walker

PLOS Pathogens: published September 1, 2015 | https://doi.org/10.1371/journal.ppat.1005143

Flavodoxin-Like Proteins Protect Candida albicans from Oxidative Stress and Promote Virulence

Lifang Li, Shamoon Naseem, Sahil Sharma, James B. Konopka

PLOS Pathogens: published September 1, 2015 | https://doi.org/10.1371/journal.ppat.1005147

Structural and Functional Characterization of Anti-A33 Antibodies Reveal a Potent Cross-Species Orthopoxviruses Neutralizer

Michael H. Matho, Andrew Schlossman, Xiangzhi Meng, Mohammed Rafii-El-Idrissi Benhnia, Thomas Kaever, Mark Buller, Konstantin Doronin, Scott Parker, Bjoern Peters, Shane Crotty, Yan Xiang, Dirk M. Zajonc

PLOS Pathogens: published September 1, 2015 | https://doi.org/10.1371/journal.ppat.1005148

Retraction: Extreme Resistance as a Host Counter-counter Defense against Viral Suppression of RNA Silencing

Raphaël Sansregret, Vanessa Dufour, Mathieu Langlois, Fouad Daayf, Patrice Dunoyer, Olivier Voinnet, Kamal Bouarab

PLOS Pathogens: published September 22, 2015 | https://doi.org/10.1371/journal.ppat.1005207

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