February 2007

Neutrophil granulocytes drag and phagocytose conidia of Aspergillus fumigatus. The electron microscope image shows a neutrophil (grey) with several attached conidia (green) (see Behnsen et al).

Image Credit: Photograph provided by Priyanka Narang, Manfred Rohde, and Matthias Gunzer, Helmholtz Centre for Infection Research.

Opinions

A Veterinary Twist on Pathogen Biology

Massimo Palmarini

PLOS Pathogens: published February 23, 2007 | https://doi.org/10.1371/journal.ppat.0030012

The Toxoplasma Kinase ROP18: An Active Member of a Degenerate Family

Anthony P Sinai

PLOS Pathogens: published February 16, 2007 | https://doi.org/10.1371/journal.ppat.0030016

Research Articles

Environmental Dimensionality Controls the Interaction of Phagocytes with the Pathogenic Fungi Aspergillus fumigatus and Candida albicans

Judith Behnsen, Priyanka Narang, Mike Hasenberg, Frank Gunzer, Ursula Bilitewski, Nina Klippel, Manfred Rohde, Matthias Brock, Axel A Brakhage, Matthias Gunzer

PLOS Pathogens: published February 2, 2007 | https://doi.org/10.1371/journal.ppat.0030013

ROP18 Is a Rhoptry Kinase Controlling the Intracellular Proliferation of Toxoplasma gondii

Hiba El Hajj, Maryse Lebrun, Stefan T Arold, Henri Vial, Gilles Labesse, Jean François Dubremetz

PLOS Pathogens: published February 16, 2007 | https://doi.org/10.1371/journal.ppat.0030014

Newly Synthesized APOBEC3G Is Incorporated into HIV Virions, Inhibited by HIV RNA, and Subsequently Activated by RNase H

Vanessa B Soros, Wes Yonemoto, Warner C Greene

PLOS Pathogens: published February 9, 2007 | https://doi.org/10.1371/journal.ppat.0030015

A New Inhibitor of Apoptosis from Vaccinia Virus and Eukaryotes

Caroline Gubser, Daniele Bergamaschi, Michael Hollinshead, Xin Lu, Frank J. M van Kuppeveld, Geoffrey L Smith

PLOS Pathogens: published February 23, 2007 | https://doi.org/10.1371/journal.ppat.0030017

Antifungal Chemical Compounds Identified Using a C. elegans Pathogenicity Assay

Julia Breger, Beth Burgwyn Fuchs, George Aperis, Terence I Moy, Frederick M Ausubel, Eleftherios Mylonakis

PLOS Pathogens: published February 2, 2007 | https://doi.org/10.1371/journal.ppat.0030018

Characterization of a Structural Intermediate of Flavivirus Membrane Fusion

Karin Stiasny, Christian Kössl, Jean Lepault, Félix A Rey, Franz X Heinz

PLOS Pathogens: published February 16, 2007 | https://doi.org/10.1371/journal.ppat.0030020

Yeast Functional Genomic Screens Lead to Identification of a Role for a Bacterial Effector in Innate Immunity Regulation

Roger W Kramer, Naomi L Slagowski, Ngozi A Eze, Kara S Giddings, Monica F Morrison, Keri A Siggers, Michael N Starnbach, Cammie F Lesser

PLOS Pathogens: published February 16, 2007 | https://doi.org/10.1371/journal.ppat.0030021

A Link between Virulence and Homeostatic Responses to Hypoxia during Infection by the Human Fungal Pathogen Cryptococcus neoformans

Cheryl D Chun, Oliver W Liu, Hiten D Madhani

PLOS Pathogens: published February 23, 2007 | https://doi.org/10.1371/journal.ppat.0030022

The Role of Myelin in Theiler's Virus Persistence in the Central Nervous System

Jean-Pierre Roussarie, Claude Ruffié, Michel Brahic

PLOS Pathogens: published February 16, 2007 | https://doi.org/10.1371/journal.ppat.0030023

Mechanism of Ad5 Vaccine Immunity and Toxicity: Fiber Shaft Targeting of Dendritic Cells

Cheng Cheng, Jason G. D Gall, Wing-pui Kong, Rebecca L Sheets, Phillip L Gomez, C. Richter King, Gary J Nabel

PLOS Pathogens: published February 23, 2007 | https://doi.org/10.1371/journal.ppat.0030025

Cover

**Neutrophil and Aspergillus fumigatus conidia**