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Correction: RVFV virulence factor NSs triggers the mitochondrial MCL-1-BAK axis to activate pathogenic NLRP3 pyroptosis

  • Zhenqiong Guan,
  • Huiling Li,
  • Chongtao Zhang,
  • Ziyan Huang,
  • Meidi Ye,
  • Yulan Zhang,
  • Shufen Li,
  • Ke Peng

S1 Fig is incorrect. Please view the correct S1 Fig below.

Supporting information

S1 Fig. RVFV infection induces cell death.

Related to Fig 1. (A and B) Representative images of cell death determined by PI staining in THP-1PMA cells infected with RVFV (MOI = 5) with indicated time (A) and indicated MOI for 24 h (B). BF, bright field. Scale bar, 100 μm. (C and D) Immunoblot analysis of pMLKL in THP-1PMA cells treated with L/S/Z (1 μg/mL LPS, 2.5 μM SM-164, 100 μM Z-VAD) for 6 h, or infected with RVFV (MOI = 5) with indicated time (C) and indicated MOI for 24 h (D). Immunoblot results are representative of three independent experiments.

https://doi.org/10.1371/journal.ppat.1013113.s001

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Reference

  1. 1. Guan Z, Li H, Zhang C, Huang Z, Ye M, Zhang Y, et al. RVFV virulence factor NSs triggers the mitochondrial MCL-1-BAK axis to activate pathogenic NLRP3 pyroptosis. PLoS Pathog. 2024;20(8):e1012387. pmid:39213434