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Open Access

Correction

Correction: A screen of drug-like molecules identifies chemically diverse electron transport chain inhibitors in apicomplexan parasites

  • Jenni A. Hayward,
  • F. Victor Makota,
  • Daniela Cihalova,
  • Rachel A. Leonard,
  • Esther Rajendran,
  • Soraya M. Zwahlen,
  • Laura Shuttleworth,
  • Ursula Wiedemann,
  • Christina Spry,
  • Kevin J. Saliba,
  • Alexander G. Maier,
  • Giel G. van Dooren

In the Abstract, one of the compounds referenced is incorrectly named MMV024937. The correct compound is MMV024397.

Also, in Fig 9, the x axis of panel H is incorrectly labelled as MMV024937. The authors have provided a corrected version here.

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Fig 9. Assessing the activity of ETC inhibitors against ELQ-300-resistant T. gondii parasites.

(A-I) Dose-response curves depicting the percent proliferation of ELQ-300-resistant (ELQR, blue) T. gondii parasites, or the corresponding ELQ-300-sensitive parental strain (ELQS, black), in the presence of increasing concentrations of (A) ELQ-300, (B) antimycin A, (C) atovaquone, (D) buparvaquone, (E) auranofin, (F) trifloxystrobin, (G) azoxystrobin, (H) MMV024397, or (I) MMV688853. Values are expressed as a percent of the average fluorescence from a no-drug control at mid-log phase growth in the fluorescence proliferation assay, and represent the mean ± SEM of three independent experiments performed in triplicate; error bars that are not visible are smaller than the symbol. Inset bar graphs depict the EC50 ± SEM (nM) of three independent experiments. Paired t-tests were performed and p-values are shown.

https://doi.org/10.1371/journal.ppat.1011987.g001

Reference

  1. 1. Hayward JA, Makota FV, Cihalova D, Leonard RA, Rajendran E, Zwahlen SM, et al. (2023) A screen of drug-like molecules identifies chemically diverse electron transport chain inhibitors in apicomplexan parasites. PLoS Pathog 19(7): e1011517. pmid:37471441

Citation: Hayward JA, Makota FV, Cihalova D, Leonard RA, Rajendran E, Zwahlen SM, et al. (2024) Correction: A screen of drug-like molecules identifies chemically diverse electron transport chain inhibitors in apicomplexan parasites. PLoS Pathog 20(2): e1011987. https://doi.org/10.1371/journal.ppat.1011987

Published: February 1, 2024

Copyright: © 2024 Hayward et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.