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Correction

Correction: Broadly directed SARS-CoV-2-specific CD4+ T cell response includes frequently detected peptide specificities within the membrane and nucleoprotein in patients with acute and resolved COVID-19

  • Janna Heide,
  • Sophia Schulte,
  • Matin Kohsar,
  • Thomas Theo Brehm,
  • Marissa Herrmann,
  • Hendrik Karsten,
  • Matthias Marget,
  • Sven Peine,
  • Alexandra M. Johansson,
  • Alessandro Sette,
  • Marc Lütgehetmann,
  • William W. Kwok,
  • John Sidney,
  • Julian Schulze zur Wiesch
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In Table 6, the 4th column of HLA alleles, the allele for DQB1 is missing a number. The correct column heading is: DQA1*05:01/DQB1*03:01. Please see the correct Table 6 below.

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Table 6. In vitro binding capacity of 14 SARS-CoV-2-specific peptides to 22 frequent HLA class II MHC molecules.

Binding capacities are expressed as IC50 nM values measured in classical in vitro binding assays based on inhibition of binding of a high affinity radiolabeled ligand to purified HLA molecules. High affinity binding is defined as IC50 < 1,000 nM and highlighted by bold font. For reasons of comprehensibility, values larger than 40,000 nM are indicated by a dash. The total number of alleles bound as well as the response frequency (RF) of the responding peptide is shown. Mem_P30 and Mem_P36, with the highest RFs, bound to 12 and 13 HLA molecules, respectively.

https://doi.org/10.1371/journal.ppat.1010220.t001

Reference

  1. 1. Heide J, Schulte S, Kohsar M, Brehm TT, Herrmann M, Karsten H, et al. (2021) Broadly directed SARS-CoV-2-specific CD4+ T cell response includes frequently detected peptide specificities within the membrane and nucleoprotein in patients with acute and resolved COVID-19. PLoS Pathog 17(9): e1009842. pmid:34529740

Citation: Heide J, Schulte S, Kohsar M, Brehm TT, Herrmann M, Karsten H, et al. (2022) Correction: Broadly directed SARS-CoV-2-specific CD4+ T cell response includes frequently detected peptide specificities within the membrane and nucleoprotein in patients with acute and resolved COVID-19. PLoS Pathog 18(1): e1010220. https://doi.org/10.1371/journal.ppat.1010220

Published: January 5, 2022

Copyright: © 2022 Heide et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.