Figures
SOX9 shapes hepatic granuloma architecture in schistosomiasis infection
Representative Picrosirius Red staining of fibrillar collagen in hepatic granulomas from (LEFT) wild-type and (RIGHT) SOX9-deficient mice, revealing the essential role of SOX9 in organising a fibrotic barrier around Schistosoma mansoni eggs. In the absence of SOX9, granulomas are disorganised and poorly contained, leading to diffuse liver injury. Su et al. 2025
Image Credit: Karen Piper Hanley and Elliot Jokl
Citation: (2025) PLoS Pathogens Issue Image | Vol. 21(6) July 2025. PLoS Pathog 21(6): ev21.i06. https://doi.org/10.1371/image.ppat.v21.i06
Published: July 2, 2025
Copyright: © 2025 . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Representative Picrosirius Red staining of fibrillar collagen in hepatic granulomas from (LEFT) wild-type and (RIGHT) SOX9-deficient mice, revealing the essential role of SOX9 in organising a fibrotic barrier around Schistosoma mansoni eggs. In the absence of SOX9, granulomas are disorganised and poorly contained, leading to diffuse liver injury. Su et al. 2025
Image Credit: Karen Piper Hanley and Elliot Jokl