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Dormant Pseudomonas aeruginosa bacteria colonize host tissues silently
Dormant Pseudomonas aeruginosa bacteria (green) colonize tissues as single cells that can be observed here through the Drosophila cuticle, following their escape from the digestive tract in a newly developed latent infection model. They are tolerant to antibiotic treatments and retain their potential for virulence. Melanization, an arthropod-specific host defense plays a key role in the establishment of latency. This study underscores the plasticity of P. aeruginosa behavior in vivo depending on the infection route. Chen et al
Image Credit: Jing Chen
Citation: (2024) PLoS Pathogens Issue Image | Vol. 20(6) July 2024. PLoS Pathog 20(6): ev20.i06. https://doi.org/10.1371/image.ppat.v20.i06
Published: July 1, 2024
Copyright: © 2024 . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Dormant Pseudomonas aeruginosa bacteria (green) colonize tissues as single cells that can be observed here through the Drosophila cuticle, following their escape from the digestive tract in a newly developed latent infection model. They are tolerant to antibiotic treatments and retain their potential for virulence. Melanization, an arthropod-specific host defense plays a key role in the establishment of latency. This study underscores the plasticity of P. aeruginosa behavior in vivo depending on the infection route. Chen et al
Image Credit: Jing Chen