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PLoS Pathogens Issue Image | Vol. 19(4) May 2023

New insights in mechanisms of helminth larvae trapping in the small intestine

The immunofluorescence picture shows a trapped larva of the murine intestinal helminth Heligmosomoides polygyrus bakeri (Hpb) in the small intestinal submucosa of a Ly5.1 Balb/c wild-type mouse on day 9 after secondary Hpb infection. Alternatively activated macrophages, defined as Relm-α+ (red) and CD68+ (green), are surrounding the trapped larva in the granuloma structure. Westermann et al 2023

Image Credit: Stefanie Westermann

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New insights in mechanisms of helminth larvae trapping in the small intestine

The immunofluorescence picture shows a trapped larva of the murine intestinal helminth Heligmosomoides polygyrus bakeri (Hpb) in the small intestinal submucosa of a Ly5.1 Balb/c wild-type mouse on day 9 after secondary Hpb infection. Alternatively activated macrophages, defined as Relm-α+ (red) and CD68+ (green), are surrounding the trapped larva in the granuloma structure. Westermann et al 2023

Image Credit: Stefanie Westermann

https://doi.org/10.1371/image.ppat.v19.i04.g001