Figures
Macrophages infected by Toxoplasma gondii parasites
Toxoplasma gondii is a single-celled parasite that grows inside a specialised vacuole compartment within a host cell. This vacuole is protected from host innate immune responses by parasite effector proteins that are secreted into the host cell. This image shows T. gondii parasites expressing mCherry (yellow) growing inside murine bone marrow-derived macrophages stained with CellMask (magenta) and DAPI (blue). Thousands of such images are taken and used to quantify the resistance of different strains of T. gondii to clearance by the host cell. Butterworth et al. 2022
Image Credit: Simon Butterworth
Citation: (2023) PLoS Pathogens Issue Image | Vol. 18(12) January 2023. PLoS Pathog 18(12): ev18.i12. https://doi.org/10.1371/image.ppat.v18.i12
Published: January 5, 2023
Copyright: © 2023 . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Toxoplasma gondii is a single-celled parasite that grows inside a specialised vacuole compartment within a host cell. This vacuole is protected from host innate immune responses by parasite effector proteins that are secreted into the host cell. This image shows T. gondii parasites expressing mCherry (yellow) growing inside murine bone marrow-derived macrophages stained with CellMask (magenta) and DAPI (blue). Thousands of such images are taken and used to quantify the resistance of different strains of T. gondii to clearance by the host cell. Butterworth et al. 2022
Image Credit: Simon Butterworth