Figures
A viral amphipathic helix targets soluble proteins to ER membranes
An amphipathic alpha-helix from the replication protein 1a of brome mosaic virus (BMV) targets a fluorescent protein to the Endoplasmic Reticulum (ER) membranes (pointed by an arrow), in the tobacco Nicotiana benthamiana cells. These membranes are the place where BMV 1a protein targets to form viral replication complexes. The helix is functionally conserved among several members of a superfamily including viruses that infect humans, animals, and plants.
Image Credit: Wenhao Zhao, School of Plant and Environmental Sciences, Virginia Tech
Citation: (2022) PLoS Pathogens Issue Image | Vol. 18(9) September 2022. PLoS Pathog 18(9): ev18.i09. https://doi.org/10.1371/image.ppat.v18.i09
Published: September 30, 2022
Copyright: © 2022 . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
An amphipathic alpha-helix from the replication protein 1a of brome mosaic virus (BMV) targets a fluorescent protein to the Endoplasmic Reticulum (ER) membranes (pointed by an arrow), in the tobacco Nicotiana benthamiana cells. These membranes are the place where BMV 1a protein targets to form viral replication complexes. The helix is functionally conserved among several members of a superfamily including viruses that infect humans, animals, and plants.
Image Credit: Wenhao Zhao, School of Plant and Environmental Sciences, Virginia Tech