Figures
The distribution of ATG8-puncta in the midgut epithelial cells from rice gall dwarf virus infected insects.
Rice gall dwarf virus (RGDV), an important rice reovirus, hijacks autophagosomes to traverse multiple insect membrane barriers in the midgut and salivary gland of leafhopper vector to enhance viral spread. In virus-infected midgut epithelial cells, ATG8 redistributed into discrete puncta, which were co-localized with viral antigens. Such virus-containing double-membraned autophagosomes are prevented from degradation, resulting in increased viral propagation. Jia et al.
Image Credit: Dongsheng Jia
Citation: (2022) PLoS Pathogens Issue Image | Vol. 18(5) May 2022. PLoS Pathog 18(5): ev18.i05. https://doi.org/10.1371/image.ppat.v18.i05
Published: May 31, 2022
Copyright: © 2022 . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Rice gall dwarf virus (RGDV), an important rice reovirus, hijacks autophagosomes to traverse multiple insect membrane barriers in the midgut and salivary gland of leafhopper vector to enhance viral spread. In virus-infected midgut epithelial cells, ATG8 redistributed into discrete puncta, which were co-localized with viral antigens. Such virus-containing double-membraned autophagosomes are prevented from degradation, resulting in increased viral propagation. Jia et al.
Image Credit: Dongsheng Jia