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PLoS Pathogens Issue Image | Vol. 17(8) August 2021

Focus of chronic Trypanosoma cruzi infection in the muscular layer of the colon wall

The image is a compressed, full-thickness z-stack of the colonic musclar wall from a mouse chronically infected with Trypanosoma cruzi. It shows a rare nest of amastigote parasites expressing a luciferase-mNeonGreen dual reporter protein (green). Neurons of the enteric nervous system, damage to which underlies the development of the digestive form of Chagas disease, are shown in magenta (neuron-specific beta-tubulin III, TuJ1+). DNA was labelled with Hoechst 33342 (white). Khan et al.

Image Credit: Lewis M, Khan A, 2021

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Focus of chronic Trypanosoma cruzi infection in the muscular layer of the colon wall

The image is a compressed, full-thickness z-stack of the colonic musclar wall from a mouse chronically infected with Trypanosoma cruzi. It shows a rare nest of amastigote parasites expressing a luciferase-mNeonGreen dual reporter protein (green). Neurons of the enteric nervous system, damage to which underlies the development of the digestive form of Chagas disease, are shown in magenta (neuron-specific beta-tubulin III, TuJ1+). DNA was labelled with Hoechst 33342 (white). Khan et al.

Image Credit: Lewis M, Khan A, 2021

https://doi.org/10.1371/image.ppat.v17.i08.g001