Figures
Bartonella effector protein C mediates actin stress fiber formation via recruitment of GEF-H1 to the plasma membrane.
Fluorescence microscopy image of HeLa cells infected with a Bartonella henselae strain deleted for all genes encoding the T4SS-translocated Bartonella effector proteins BepA-BepG in the chromosome that expresses BepC from a plasmid. Bacteria (red, visualized with an anti-B. henselae antibody) translocate BepC into the host cells, resulting in actin stress fiber formation (green, visualized by phalloidin staining). Nuclei were stained with DAPI (blue). Marlaire and Dehio.
Image Credit: Marlaire S and Dehio C. (2021)
Citation: (2021) PLoS Pathogens Issue Image | Vol. 17(1) February 2021. PLoS Pathog 17(1): ev17.i01. https://doi.org/10.1371/image.ppat.v17.i01
Published: February 2, 2021
Copyright: © 2021 . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Fluorescence microscopy image of HeLa cells infected with a Bartonella henselae strain deleted for all genes encoding the T4SS-translocated Bartonella effector proteins BepA-BepG in the chromosome that expresses BepC from a plasmid. Bacteria (red, visualized with an anti-B. henselae antibody) translocate BepC into the host cells, resulting in actin stress fiber formation (green, visualized by phalloidin staining). Nuclei were stained with DAPI (blue). Marlaire and Dehio.
Image Credit: Marlaire S and Dehio C. (2021)