Figures
Persistent apoptotic lesion of the cerebellum in ZikV convalescent CNS.
Image shows one of multiple foci of infection in the cerebellum of 1year old mice following a neonatal infection with Zika virus. TUNEL+, apoptotic lesion of the granular layer of the cerebellum (green) surrounded by inflammatory microglia (red). Nuclei are labelled with DAPI (blue). The persistent microgliosis surrounding the foci correlates with increased levels of inflammation cellular infiltration and chronic behavioral deficits. Ireland et al.
Image Credit: Ireland D. D. C. (2020)
Citation: (2021) PLoS Pathogens Issue Image | Vol. 16(12) January 2021. PLoS Pathog 16(12): ev16.i12. https://doi.org/10.1371/image.ppat.v16.i12
Published: January 4, 2021
Copyright: © 2021 . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Image shows one of multiple foci of infection in the cerebellum of 1year old mice following a neonatal infection with Zika virus. TUNEL+, apoptotic lesion of the granular layer of the cerebellum (green) surrounded by inflammatory microglia (red). Nuclei are labelled with DAPI (blue). The persistent microgliosis surrounding the foci correlates with increased levels of inflammation cellular infiltration and chronic behavioral deficits. Ireland et al.
Image Credit: Ireland D. D. C. (2020)