Figures
Plasmodium kinesin-8X associates with mitotic spindles and is essential for parasite proliferation and transmission
Malaria parasites proliferate by closed endomitosis, with genome replication and division occurring prior to cytokinesis within a nucleus bounded by a persistent envelope. Plasmodium kinesin-8X is located on putative microtubule organising centres (MTOCs) and mitotic spindles during cell division. The kinesin-8X gene is essential during mosquito stages of the life cycle and its deletion blocks parasite transmission. The image shows an ookinete with surface protein p28 stained red, nuclear DNA stained blue and kinesin-8X-GFP stained green. Zeeshan et al.
Image Credit: M Zeeshan and Rita Tewari (2019)
Citation: (2019) PLoS Pathogens Issue Image | Vol. 15(10) November 2019. PLoS Pathog 15(10): ev15.i10. https://doi.org/10.1371/image.ppat.v15.i10
Published: November 5, 2019
Copyright: © 2019 . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Malaria parasites proliferate by closed endomitosis, with genome replication and division occurring prior to cytokinesis within a nucleus bounded by a persistent envelope. Plasmodium kinesin-8X is located on putative microtubule organising centres (MTOCs) and mitotic spindles during cell division. The kinesin-8X gene is essential during mosquito stages of the life cycle and its deletion blocks parasite transmission. The image shows an ookinete with surface protein p28 stained red, nuclear DNA stained blue and kinesin-8X-GFP stained green. Zeeshan et al.
Image Credit: M Zeeshan and Rita Tewari (2019)