Figures
Cell-associated respiratory syncytial virus spread via filopodia.
Respiratory epithelial A549 cells inoculated with respiratory syncytial virus (RSV) for 24 hours are stained for RSV F protein (green) and cellular F-actin (red); nuclei have been counterstained with DAPI (blue). This image shows the cell on the left is infected and has extensive RSV-induced filopodia that contact the uninfected cell on the right. Filamentous RSV particles can be seen on the infected cell surface and at filopodia tips. Mehedi et al.
Image Credit: Sundar Ganesan, Margery Smelkinson, and Juraj Kabat, Biological Imaging Section, National Institute of Allergy and Infectious Diseases (NIAID) and Masfique Mehedi, Laboratory of Infectious Diseases, NIAID, National Institutes of Health, Bethesda, MD.
Citation: (2016) PLoS Pathogens Issue Image | Vol. 12(12) December 2016. PLoS Pathog 12(12): ev12.i12. https://doi.org/10.1371/image.ppat.v12.i12
Published: December 30, 2016
Copyright: © 2016 Mehedi. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Respiratory epithelial A549 cells inoculated with respiratory syncytial virus (RSV) for 24 hours are stained for RSV F protein (green) and cellular F-actin (red); nuclei have been counterstained with DAPI (blue). This image shows the cell on the left is infected and has extensive RSV-induced filopodia that contact the uninfected cell on the right. Filamentous RSV particles can be seen on the infected cell surface and at filopodia tips. Mehedi et al.
Image Credit: Sundar Ganesan, Margery Smelkinson, and Juraj Kabat, Biological Imaging Section, National Institute of Allergy and Infectious Diseases (NIAID) and Masfique Mehedi, Laboratory of Infectious Diseases, NIAID, National Institutes of Health, Bethesda, MD.