Figures
Macrophages in a liver granuloma around Schistosoma mansoni eggs.
Alternatively activated macrophages regulate immune responses in the granulomas around S. mansoni eggs. These cells are an important source of retinoic acid and enhance the differentiation of Foxp3+ T cell differentiation (see Broadhurst et al., doi:10.1371/journal.ppat.1002883). By intravital confocal imaging, autofluorescent eggs are observed in red, hepatocyte nuclei in blue, and CX3CR1+ macrophages in green.
Image Credit: Natasha M. Girgis, New York University Langone Medical Center.
Citation: (2012) PLoS Pathogens Issue Image | Vol. 8(8) August 2012. PLoS Pathog 8(8): ev08.i08. https://doi.org/10.1371/image.ppat.v08.i08
Published: August 30, 2012
Copyright: © Broadhurst et al. . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Alternatively activated macrophages regulate immune responses in the granulomas around S. mansoni eggs. These cells are an important source of retinoic acid and enhance the differentiation of Foxp3+ T cell differentiation (see Broadhurst et al., doi:10.1371/journal.ppat.1002883). By intravital confocal imaging, autofluorescent eggs are observed in red, hepatocyte nuclei in blue, and CX3CR1+ macrophages in green.
Image Credit: Natasha M. Girgis, New York University Langone Medical Center.