Figures
Localization of murine gammaherpesvirus 68 M3 transcripts in lung tissue.
Wood mice (Apodemus sylvaticus) are a natural host for murine gammaherpesvirus 68 (MHV-68). A captive-bred wood mouse was infected intranasally with MHV-68. At day 7 post-infection, lung tissue was analyzed by RNA in situ hybridisation using probes specific for the MHV-68 M3 open reading frame, which encodes a viral chemokine binding protein. M3 transcripts (dark purple signals) were detected within lymphocytes in perivascular infiltrates and circulating lymphocytes attached to endothelial cells of an artery (see Hughes et al., doi:10.1371/journal.ppat.1001321).
Image Credit: Anja Kipar, University of Liverpool
Citation: (2011) PLoS Pathogens Issue Image | Vol. 7(3) March 2011. PLoS Pathog 7(3): ev07.i03. https://doi.org/10.1371/image.ppat.v07.i03
Published: March 31, 2011
Copyright: © 2011 Kipar. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Wood mice (Apodemus sylvaticus) are a natural host for murine gammaherpesvirus 68 (MHV-68). A captive-bred wood mouse was infected intranasally with MHV-68. At day 7 post-infection, lung tissue was analyzed by RNA in situ hybridisation using probes specific for the MHV-68 M3 open reading frame, which encodes a viral chemokine binding protein. M3 transcripts (dark purple signals) were detected within lymphocytes in perivascular infiltrates and circulating lymphocytes attached to endothelial cells of an artery (see Hughes et al., doi:10.1371/journal.ppat.1001321).
Image Credit: Anja Kipar, University of Liverpool