Figures
Localization of CD11cYFP dendritic calls and OT1GFP cells in the lymph node following infection with Toxoplasma gondii.
3-D projection of a z stack from the lymph node of a CDllcYFP mouse that was adoptively transferred with ovalbumin-specific CD8+ GFP+ T cells and infected with T. gondii expressing ovalbumin. An increased proportion of dendritic cells (yellow) and T cells (green) are associated with the sub-capsular region (capsule seen in blue) of the lymph node following infection. Also note the vacuolar structures within the dendritic cells, which are induced during infection. This image was acquired on a Leica SP5 2-photon microscope equipped with a picosecond laser and tunable internal detectors (see John et al., doi:10.1371/journal.ppat.1000505).
Image Credit: Beena John and Christopher A. Hunter, University of Pennsylvania.
Citation: (2009) PLoS Pathogens Issue Image | Vol. 5(7) July 2009. PLoS Pathog 5(7): ev05.i07. https://doi.org/10.1371/image.ppat.v05.i07
Published: July 31, 2009
Copyright: © 2009 John, Hunter. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
3-D projection of a z stack from the lymph node of a CDllcYFP mouse that was adoptively transferred with ovalbumin-specific CD8+ GFP+ T cells and infected with T. gondii expressing ovalbumin. An increased proportion of dendritic cells (yellow) and T cells (green) are associated with the sub-capsular region (capsule seen in blue) of the lymph node following infection. Also note the vacuolar structures within the dendritic cells, which are induced during infection. This image was acquired on a Leica SP5 2-photon microscope equipped with a picosecond laser and tunable internal detectors (see John et al., doi:10.1371/journal.ppat.1000505).
Image Credit: Beena John and Christopher A. Hunter, University of Pennsylvania.