Figures
Membrane ruffles triggered by the Salmonella actin-binding protein SipC are enriched with phosphatidylinositol-4,5-bisphosphate
Fluorescence micrograph of an NIH3T3 cell expressing the phosphatidylinositol-4,5-bisphosphate reporter PLCδ-PH-GFP (green) after infection with Salmonella typhimurium engineered to deliver augmented levels of SipC (see Cain et al., e1000037). Cells are co-stained with Texas Red-conjugated phalloidin (red) and DAPI (blue) to visualize F-actin and cell nuclei and bacteria, respectively.
Image Credit: Image generated by Robert Cain.Citation: (2008) PLoS Pathogens Issue Image | Vol. 4(4) April 2008. PLoS Pathog 4(4): ev04.i04. https://doi.org/10.1371/image.ppat.v04.i04
Published: April 25, 2008
Copyright: © 2008 Cain et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Fluorescence micrograph of an NIH3T3 cell expressing the phosphatidylinositol-4,5-bisphosphate reporter PLCδ-PH-GFP (green) after infection with Salmonella typhimurium engineered to deliver augmented levels of SipC (see Cain et al., e1000037). Cells are co-stained with Texas Red-conjugated phalloidin (red) and DAPI (blue) to visualize F-actin and cell nuclei and bacteria, respectively.
Image Credit: Image generated by Robert Cain.