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PLoS Pathogens Issue Image | Vol. 4(1) January 2008

H. pylori binds ABO blood group antigens

The carcinogen and peptic ulcer pathogen Helicobacter pylori binds the secretor status ABO blood group antigens. Antigen A is on the left, antigen B is at the bottom right, and antigen Leb (blood group O) is at the top right. Fucose residues are shown in green, GalNAcα1.3 (in Aleb) and Galα1.3 (in BLeb) in purple, and carbon/hydrogen in gray (see Lindén et al, e2).

Image Credit: We thank P.-G. Nyholm for structural predictions of blood group antigens.

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H. pylori binds ABO blood group antigens

The carcinogen and peptic ulcer pathogen Helicobacter pylori binds the secretor status ABO blood group antigens. Antigen A is on the left, antigen B is at the bottom right, and antigen Leb (blood group O) is at the top right. Fucose residues are shown in green, GalNAcα1.3 (in Aleb) and Galα1.3 (in BLeb) in purple, and carbon/hydrogen in gray (see Lindén et al, e2).

Image Credit: We thank P.-G. Nyholm for structural predictions of blood group antigens.

https://doi.org/10.1371/image.ppat.v04.i01.g001