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PLoS Pathogens Issue Image | Vol. 3(3) March 2007

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HIV-infected macrophage

Electron micrograph of a thin section through an HIV-1-infected macrophage. The membrane-impermeant dye ruthenium red forms an electron-dense coat on the plasma membrane. Thus, it becomes obvious that virus particles, which are also stained with ruthenium red, accumulate in a deep invagination that is continuous with the plasma membrane (see Welsch et al).

Image Credit: Photograph provided by Anja Habermann, Heidelberg University.

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HIV-infected macrophage

Electron micrograph of a thin section through an HIV-1-infected macrophage. The membrane-impermeant dye ruthenium red forms an electron-dense coat on the plasma membrane. Thus, it becomes obvious that virus particles, which are also stained with ruthenium red, accumulate in a deep invagination that is continuous with the plasma membrane (see Welsch et al).

Image Credit: Photograph provided by Anja Habermann, Heidelberg University.

https://doi.org/10.1371/image.ppat.v03.i03.g001