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Fig 1.

Comparative genomic analysis of defence-related genes in wild and domesticated barley (A) and Solanum (B).

Abbreviations are listed in S1 Table. (C) Biosynthetic gene clusters in Solanum species. The phylogenetic tree shows species relationships. In the centre, arrows represent co-located genes with standardised lengths and are colour-coded by gene class. The heatmap summarises copy numbers per gene family, considering only genes clustered on the same chromosome. Hierarchical orthogroups (HOGs) were inferred with OrthoFinder [35]. CYP: cytochrome P450 monooxygenases; 24ISO: sterol Δ24-isomerase; ODD: 2-oxoglutarate-dependent dioxygenase; ST: sulfotransferase; SDR: short-chain dehydrogenases/reductases; ASAT: acylsugar acyltransferase.

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Fig 2.

Integrating pan-genomes, wild relative screening and genome editing to develop improved disease-resistant crops.

Schematic overview of how diversity resources, phenotyping, pan-genome analyses and functional validation inform breeding, precision editing and de novo domestication. Created in BioRender. Kamal, N. (2026) https://BioRender.com/4mtdik9.

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