Fig 1.
Ideal animal model that can support the full life cycle of Entamoeba histolytica.
From top left to bottom right: (1) fewer animals used to maintain virulence; (2) less need for continuous passaging; (3) new detection methods for food safety and patient diagnostics; (4) model for drug screening; (5) focus on host response to developmental changes of the parasite in vivo; and (6) could serve as potential model to pioneer in vivo studies of E. histolytica with other pathogenic and nonpathogenic protozoans. Figure created with BioRender.com.