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Fig 1.

Schematic of study design showing timelines, environmental controls and monitoring, physical segregation arrangements, exposure intervention, and volunteer movements during quarantine study.

DFA: direct fluorescence assay; RH: relative humidity; NPS: nasopharyngeal swab.

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Fig 2.

Trial profile.

Intervention Recipients: wore face shields, used hand sanitizer every 15 min and only allowed to touch face with single-use wooden spatula; Control Recipients: did not use face shields or the specified hand hygiene protocol.

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Table 1.

Infected donor status.

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Fig 3.

Viral detection in Donors by day of exposure event.

A) Columns show the proportion of all infected donors (n = 42) who were qRT-PCR positive for viral shedding for coarse (>5μm) and fine (≤5μm) aerosols, and nasopharyngeal swabs. B) Mean and standard deviation error bars for qRT-PCR cycle threshold values from the positive nasopharyngeal swabs (n = 19 on day 1; n = 34 on day 2; n = 35 on day 3; n = 31 on day 4). C) Virus quantified (log10 RNA copies) from detectable exhaled coarse (n = 6) and fine (n = 14) breath aerosols by qRT-PCR; the boxes show the inner-quartile range (IQR) with a band to indicate the median, and whiskers extending to highest and lowest data points within 1.5 IQR.

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Table 2.

Exhaled breath viral RNA detection and copy number among infected donors by quarantine event and aerosol fraction.

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Table 3.

Recipient status.

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