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Fig 1.

Schematic representation of the two pathways through which the gut microbiome putatively promotes liver cancer via antitumor immunosuppression.

BAs marked with an asterisk are from rats and mice only. BA, bile acid; CA, cholic acid; CDCA, chenodeoxycholic acid; COX2, cyclooxygenase 2; CXCL16, chemokine (C-X-C motif) ligand 16; CXCR6, C-X-C chemokine receptor type 6; DCA, deoxycholic acid; GLCA, glucuronic acid; HCA, hyocholic acid; HDCA, hyodeoxycholic acid; LCA, lithocholic acid; LTA, lipoteichoic acid; MCA, muricholic acid; MDCA, murideoxycholic acid; PGE2, prostaglandin E2; PTGER4, prostaglandin E receptor 4; UDCA, ursodeoxycholic acid.

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