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Fig 1.

Intracellular bacterial spread from cell to cell.

Steps supporting the intracellular dissemination of Listeria monocytogenes [46]. Important variations in this process during Shigella flexneri, Rickettsia spp., and Burkholderia spp. dissemination are discussed in this review.

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Fig 2.

Host and bacterial factors that facilitate cell-to-cell spread.

For each step of spread, the key factors involved are shown for L. monocytogenes, S. flexneri, Rickettsia spp., and Burkholderia spp. Host factors are indicated in red and bacterial factors are indicated in green. ERM, Ezrin, Radixin, Moesin Family Proteins; LLO, Listeriolysin O; Plc, phospholipase.

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