Figure 1.
Genomic comparisons between var. grubii and var. neoformans reveal relatively few rearrangements.
Since divergence 18.5 million years ago, the two varieties of C. neoformans have maintained a largely syntenic genome structure with only a few inversions specific to each variety (marked with arrows). Comparisons also uncovered several strain-specific events: a translocation in the case of the var. grubii type strain H99 and telomere-telomere fusion and introgression in the case of var. neoformans JEC21.