Figure 1.
Map of Bolivia showing location of the Chapare virus-associated HF case relative to the Beni region where Machupo virus-associated HF cases originate.
The Beni Department boundary is depicted by the checkered line. Multiple Machupo isolates have been recorded from the Beni Department. The single Latino and Chapare virus locations are labeled and represented as dots.
Table 1.
Differences between Chapare virus and its closest relative, Sabiá, are similar to differences between other distinct species of arenavirus
Table 2.
Differences among strains of the same species of arenavirus
Figure 2.
Phylogenetic analysis of the complete S and L RNA segments of New World arenaviruses.
Complete S and L segments for New World arenaviruses were analyzed by Bayesian inference of phylogeny (MrBayes3.1.2) using the sequence of Pichindé virus as the outgroup. Multiple strains are grouped with small brackets and large brackets group the arenavirus Clades: A, A/Rec, B, and C. The Genbank accession numbers for the S segment analysis include: Allpahuayo (AY012686), Amapari (AF485256), Bear Canyon (AY924392), Catarina (DQ865245), Chapare (EU260463), Cupixi (AF512832), Flexal (AF485257), Guanarito (NC_005077), Junín (AY619641, NC_005081, AY746353), Latino (AF512830), Machupo (AY924208, AY619645, AY924202, NC_005078), Oliveros (U34248), Paraná (AF485261), Pichindé (NC_006447), Pirital (NC_005894), Sabiá (NC_006317), Tacaribe (NC_004293), Tamiami (AF485263), and Whitewater Arroyo (AF485264). The Genbank accession numbers used for the L segment analysis include: Allpahuayo (NC_010249), Amapari (AY924389), Bear Canyon (AY924390), Chapare (EU260464), Cupixi (NC_010252), Guanarito (NC_005082), Junín (NC_005080, AY819707, AY619640), Machupo (AY624354, NC_005079, AY619644), Oliveros (NC_010250), Pichindé (NC_006439), Pirital (NC_005897), Sabiá (NC_006313), Tacaribe (NC_004292), Tamiami (AY924393), and Whitewater Arroyo (AY924395).