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Pigs lacking Natural Killer T cells have altered cellular responses to influenza

Fig 5

Flow cytometric analysis of T cell frequencies in enzymatically digested lung tissue at 5 DPC.

(A) CD3+ T cells as a proportion of lung lymphocytes. (B) αβ T cells as a proportion of lung lymphocytes. (C) CD8αβ+ T cells as a proportion of CD3+ T cells. ANOVA and subsequent Tukey’s adjustment was used to determine a statistically significant difference (p < 0.05), and the significance between two groups is indicated by different letters. Data are represented as mean ± SEM. Symbols represent individual pigs. G1 (n = 6): CD1D − / − vaccinated and challenged; G2 (n = 6): CD1D − / + vaccinated and challenged; G3 (n = 5): CD1D − / − not vaccinated and challenged; G4 (n = 5): CD1D − / + not vaccinated and challenged; G5 (n = 3): CD1D − / + not vaccinated, not challenged.

Fig 5

doi: https://doi.org/10.1371/journal.ppat.1014094.g005