Dietary tannic acid promotes intestinal clearance of C. albicans by cross-linking hyphal chitosan
Fig 5
Analysis of differential proteins expressed in TA-treated C. albicans and the cda2Δ/Δ mutant.
(A) Principal component analysis. Plots showed protein abundance in C. albicans SC5314 (mock, black), SC5314 treated with 2 μg/ml TA (TA, red), hyphae of C. albicans SN152 (SN152-H, purple) and hyphae of cda2Δ/Δ mutants (cda2Δ/Δ-H, blue). C. albicans were cultured in RPMI1640 at 37 °C for 12 h and each principal component (PC1 and PC2) shows the variance percentage. (B) Volcano plots of the differentially expressed proteins. (C) GO enrichment analysis of the differentially expressed proteins in TA-treated C. albicans and the cda2Δ/Δ mutant. (D) Venn diagram showing the overlap of differentially expressed proteins between TA-treated C. albicans and the cda2Δ/Δ mutant. (E) Heatmap showing the changes of fungal cell wall proteins in TA-treated C. albicans and the cda2Δ/Δ mutant.