Adaptation of the Mycobacterium tuberculosis transcriptome to biofilm growth
Fig 2
Differentiation of transcriptomes between closely related populations.
Left: Whole-genome sequence phylogeny of ancestral populations used for passaging. Populations fall into two major L4 sub-lineages: L4.9 (purple) and L4.4 (orange) with SNP distances shown along each branch. Right: Number of significantly differentially expressed genes (DEGs) between biofilm and planktonic conditions for each ancestral population. Note that the analysis of ancestral MT49 is not included because only one biological replicate was available under planktonic conditions.