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Guanosine inhibits hepatitis C virus replication and increases indel frequencies, associated with altered intracellular nucleotide pools

Table 1

Effects of nucleosides on cell viability and HCV replication.

CC₅₀, IC₅₀, and therapeutic index (TI, CC₅₀/IC₅₀) values are shown for Adenosine (Ade), Cytidine (Cyt), Guanosine (Gua), and Uridine (Uri) in Huh-7.5 reporter cells.

doi: https://doi.org/10.1371/journal.ppat.1010210.t001