Quantification of T-cell dynamics during latent cytomegalovirus infection in humans
Fig 5
Association between T-cell production rates and expression of senescence, proliferation, and apoptosis markers.
The estimated average production rates of different CD4+ and CD8+ T-cell subsets as estimated by heavy water labelling were plotted against their expression (% positive) of CD57, KLRG-1, CD28, Ki-67, and Bcl-2. Data points of donor E04 are circled in the Ki-67 graph. Correlation was tested by Spearman’s correlation, P-values and r-values are indicated in the graphs. Different symbols represent different memory subpopulations.