Phase separation and DAXX redistribution contribute to LANA nuclear body and KSHV genome dynamics during latency and reactivation
Fig 9
Model of LLPS-driven LANA-NB formation.
Dynamic LANA-NB structures form through the combined actions of the structured DNA binding domain (DBD), KSHV terminal repeat DNA templated oligomerization, and the low complexity, multivalent N-terminal domain interactions driving LLPS.