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Prophages integrating into prophages: A mechanism to accumulate type III secretion effector genes and duplicate Shiga toxin-encoding prophages in Escherichia coli

Fig 5

Locations of the attB-in-PP sequences in prophages and the prophage genome regions homologous to E. coli chromosome regions.

Three loci in the E. coli chromosome showing sequence homology to three identified attB-in-PP sequences and their flanking sequences are shown at the top. The left- and right-end regions of representative prophages that contained the att-in-PP sequences are shown below. Homologous sequences are indicated by the same color. The color used for each attB-in-PP sequence is the same as that used in Figs 4 and S5. See these figures for the details of “PPompWs” and “prophages in PPmlrA/PPydfJ” and S9 Fig for information on the prophages in mlrA, ydfJ, ssrA, and yecE and PPompW. Alignments of the attB-in-PP_1 and attB-in-PP_2 sequences and their flanking sequences with corresponding chromosome sequences are shown in S8 and S9 Figs, respectively.

Fig 5

doi: https://doi.org/10.1371/journal.ppat.1009073.g005