The narrow-spectrum anthelmintic oxantel is a potent agonist of a novel acetylcholine receptor subtype in whipworms
Fig 6
Effect of the antagonists: dihydro-β-erythroidine (DHβE) and derquantel (der) on Tsu-ACR-16-like receptor mediated 100 μM ACh current response.
Results are given as normalized mean ± SEM inhibition of the initial current response of 100 μM ACh. DHβE produced an almost insignificant block of the Tsu-ACR-16-like receptor mediated ACh response (i.e. 7.60 ± 1.61%) and no effect was observed for der (0.16 ± 1.61%).